Bacterial toxins as pathogen weapons against phagocytes

A Do Vale, D Cabanes, S Sousa - Frontiers in microbiology, 2016 - frontiersin.org
Bacterial toxins are virulence factors that manipulate host cell functions and take over the
control of vital processes of living organisms to favor microbial infection. Some toxins directly …

[PDF][PDF] Revisiting the genus Photobacterium: taxonomy, ecology and pathogenesis

AM Labella, DR Arahal, D Castro, ML Lemos… - Int Microbiol, 2017 - revistes.iec.cat
The genus Photobacterium, one of the eight genera included in the family Vibrionaceae,
contains 27 species with valid names and it has received attention because of the …

Evolution of insect innate immunity through domestication of bacterial toxins

KI Verster, G Cinege, Z Lipinszki… - Proceedings of the …, 2023 - National Acad Sciences
Toxin cargo genes are often horizontally transferred by phages between bacterial species
and are known to play an important role in the evolution of bacterial pathogenesis. Here, we …

A M35 family metalloprotease is required for fungal virulence against insects by inactivating host prophenoloxidases and beyond

A Huang, M Lu, E Ling, P Li, C Wang - Virulence, 2020 - Taylor & Francis
ABSTRACT A diverse family of metalloproteases (MPs) is distributed in eukaryotes.
However, the functions of MPs are still understudied. We report that seven MPs belonging to …

Unconventional structure and mechanisms for membrane interaction and translocation of the NF-κB-targeting toxin AIP56

J Lisboa, C Pereira, RD Pinto, IS Rodrigues… - Nature …, 2023 - nature.com
Bacterial AB toxins are secreted key virulence factors that are internalized by target cells
through receptor-mediated endocytosis, translocating their enzymatic domain to the cytosol …

Photobacteriosis: prevention and diagnosis

F Andreoni, M Magnani - Journal of immunology Research, 2014 - Wiley Online Library
Photobacteriosis or fish pasteurellosis is a bacterial disease affecting wild and farm fish. Its
etiological agent, the gram negative bacterium Photobacterium damselae subsp. piscicida …

The biology and the importance of Photobacterium species

IM Moi, NN Roslan, ATC Leow, MSM Ali… - Applied microbiology …, 2017 - Springer
Photobacterium species are Gram-negative coccobacilli which are distributed in marine
habitats worldwide. Some species are unique because of their capability to produce …

Metalloprotease NleC suppresses host NF-κB/inflammatory responses by cleaving p65 and interfering with the p65/RPS3 interaction

A Hodgson, EM Wier, K Fu, X Sun, H Yu… - PLoS …, 2015 - journals.plos.org
Attaching/Effacing (A/E) pathogens including enteropathogenic Escherichia coli (EPEC),
enterohemorrhagic E. coli (EHEC) and the rodent equivalent Citrobacter rodentium are …

Host manipulation by bacterial type III and type IV secretion system effector proteases

F Viana, SS Peringathara, A Rizvi… - Cellular …, 2021 - Wiley Online Library
Proteases are powerful enzymes, which cleave peptide bonds, leading most of the time to
irreversible fragmentation or degradation of their substrates. Therefore they control many …

A metalloprotease homolog venom protein from a parasitoid wasp suppresses the toll pathway in host hemocytes

Z Lin, Y Cheng, RJ Wang, J Du, O Volovych… - Frontiers in …, 2018 - frontiersin.org
Parasitoid wasps depend on a variety of maternal virulence factors to ensure successful
parasitism. Encapsulation response carried out by host hemocytes is one of the major host …