Apoptosis is now recognized as a normal feature in the development of the nervous system
and may also play a role in neurodegenerative diseases and aging. This phenomenon has …

Three routes have been identified triggering neuronal death under physiological and
pathological conditions. Excess activation of ionotropic glutamate receptors cause influx and …

Death pathways restricted to specific neuronal classes could potentially allow for precise
control of developmental neuronal death and also underlie the selectivity of neuronal loss in …

The fetal brain is sensitive to a variety of teratogens, including ethanol. We showed
previously that ethanol induced mitosis and stem cell maturation, but not death, in fetal …

Astrocytes are the main support cells of the central nervous system. They also participate in
neuroimmune reactions. In response to pathological and immune stimuli, astrocytes …

After a severe episode of ischemia, traumatic brain injury (TBI) or epilepsy, it is typical to find
necrotic cell death within the injury core. In addition, a substantial number of neurons in …

The ability of peripheral nervous system (PNS) but not central nervous system (CNS)
neurons to regenerate their axons is a striking peculiarity of higher vertebrates. Much …

Apoptosis, or programmed cell death, is a physiological form of cell death that is important
for normal embryologic development and cell turnover in adult organisms. Cumulative …

Fas (also known as CD95), a member of the tumour-necrosis receptor factor family of'death
receptors', can induce apoptosis or, conversely, can deliver growth stimulatory signals. Here …

Apoptosis, also known as programmed cell death, is the major type of cell death involved in
normal development, regeneration, proliferation and pathologic degeneration in the central …