Anti-proliferative and antitumor activity of organotin (IV) compounds. An overview of the last decade and future perspectives

CN Banti, SK Hadjikakou, T Sismanoglu… - Journal of inorganic …, 2019 - Elsevier
Organotins (IV) exhibit significant in vitro anti-proliferative activity, while the in vivo tests are
encouraging. The recent reports on the anti-proliferative activity of organotin (IV) compounds …

Anticancer activity of organotin (IV) carboxylates

MK Amir, S Khan, A Shah, IS Butler - Inorganica Chimica Acta, 2014 - Elsevier
This article provides a critical review of the anticancer activity of organotin (IV) carboxylates
in the last five years. Most of the organotin (IV) carboxylates discussed in this review have …

Cytotoxicity and DNA damage properties of tert-butylhydroquinone (TBHQ) food additive

M Eskandani, H Hamishehkar, JEN Dolatabadi - Food chemistry, 2014 - Elsevier
Tert-butylhydroquinone (TBHQ) was tested for potential cytotoxicity and genotoxicity upon
A549 lung cancer cells and Human Umbilical Vein Endothelial Cells (HUVEC). Cytotoxicity …

Novel diphenyltin (IV) complexes with carboxylato N-functionalized 2-quinolone ligands: Synthesis, characterization and in vitro anticancer studies

MP Kasalović, S Jelača, D Maksimović-Ivanić… - Journal of Inorganic …, 2024 - Elsevier
Three new diphenyltin (IV) complexes, bis (3-(4-methyl-2-oxoquinolinyl-1 (2H)-yl)
propanoato) diphenyltin (IV)(1), bis (2-(4-methyl-2-oxoquinolin-1 (2H)-yl) ethanoato) …

Formulation, characterization and cytotoxicity studies of alendronate sodium-loaded solid lipid nanoparticles

JEN Dolatabadi, H Hamishehkar, M Eskandani… - Colloids and Surfaces B …, 2014 - Elsevier
Abstract Aim Solid lipid nanoparticles (SLNs) are novel drug delivery system for drug
targeting in various routs of administration such as parenteral, oral, ophthalmic and topical …

Organotin (IV) complexes derived from Schiff base N′-[(1E)-(2-hydroxy-3-methoxyphenyl) methylidene] pyridine-4-carbohydrazone: Synthesis, in vitro cytotoxicities …

M Hong, H Geng, M Niu, F Wang, D Li, J Liu… - European journal of …, 2014 - Elsevier
Five organotin (IV) compounds were synthesized from N′-[(1E)-(2-hydroxy-3-
methoxyphenyl) methylidene] pyridine-4-carbohydrazone and the corresponding dialkyltin …

Cytotoxicity and DNA fragmentation properties of butylated hydroxyanisole

S Vandghanooni, A Forouharmehr… - DNA and cell …, 2013 - liebertpub.com
Butylated hydroxyanisole (BHA) is a synthetic phenolic food additive that is used to prevent
oils, fats, and shortenings from oxidative deterioration and rancidity. It was tested for …

Orotic acid, more than just an intermediate of pyrimidine de novo synthesis

M Löffler, EA Carrey, E Zameitat - Journal of genetics and genomics, 2015 - Elsevier
It is timely to consider the many facets of the small molecule orotic acid (OA), which is well-
known as an essential intermediate of pyrimidine de novo synthesis. In addition, it can be …

Organotin (IV) complexes derived from hydrazone ligands: Synthesis, spectral analysis, antimicrobial and molecular docking studies

N Kumar, S Asija, Y Deswal, S Saroya… - … , Sulfur, and Silicon …, 2022 - Taylor & Francis
The goal of this research work is to create a new class of diorganotin (IV) complexes with
general formula R2SnL1-4, where R= CH3, C2H5, C4H9 & C6H5, and L1-4 are the Schiff …

[HTML][HTML] Cell-based methods for determination of efficacy for candidate therapeutics in the clinical management of cancer

JL Gordon, MA Brown, MM Reynolds - Diseases, 2018 - mdpi.com
Determination of therapeutic efficacy is a major challenge in developing treatment options
for cancer. Prior to in vivo studies, candidate therapeutics are evaluated using cell-based in …