Positron emission tomography (PET) is a radiotracer imaging method that yields quantitative
images of regional in vivo biology and biochemistry. PET, now used in conjunction with …

This review addresses the specific contributions of nuclear medicine techniques, and
especially positron emission tomography (PET), for diagnosis and management of brain …

Treatment of glioblastoma (GBM), the most common primary malignant brain tumor in adults,
remains a significant unmet need in oncology. Historically, cytotoxic treatments provided …

Background The dynamics of the cellular glycolysis pathway underpin cellular function and
dysfunction, and therefore ultimately health, disease, diagnostic and therapeutic strategies …

After chemoradiotherapy for glioblastoma, pseudoprogression can occur and must be
distinguished from true progression to correctly manage glioblastoma treatment and follow …

Over the last decade, pseudoprogression as a clinically significant entity affecting both
glioma patient management and the conduct of clinical trials has been recognized as a …

A previous review published in 2012 demonstrated the role of clinical PET for diagnosis and
management of brain tumors using mainly FDG, amino acid tracers, and 18 F …

Molecular targets for the pathological vasculature are the vascular endothelial growth factor
(VEGF)/VEGF receptor axis, integrins, angiopoietins, and platelet-derived growth factor …

Several new tracers are being developed for use with PET to assess pathways that are
altered in cancers, including energy use, cellular signaling, transport, and proliferation …

Positron emission tomography (PET) is a highly quantitative imaging modality that can probe
a number of functional and biological processes, depending on the radio-labelled tracer …