[HTML][HTML] Blood culture-based diagnosis of bacteraemia: state of the art

O Opota, A Croxatto, G Prod'Hom, G Greub - Clinical Microbiology and …, 2015 - Elsevier
Blood culture remains the best approach to identify the incriminating microorganisms when
a bloodstream infection is suspected, and to guarantee that the antimicrobial treatment is …

Emerging technologies for the clinical microbiology laboratory

BW Buchan, NA Ledeboer - Clinical microbiology reviews, 2014 - Am Soc Microbiol
In this review we examine the literature related to emerging technologies that will help to
reshape the clinical microbiology laboratory. These topics include nucleic acid amplification …

Molecular diagnosis of sepsis: New aspects and recent developments

O Liesenfeld, L Lehman, KP Hunfeld… - European journal of …, 2014 - akjournals.com
By shortening the time to pathogen identification and allowing for detection of organisms
missed by blood culture, new molecular methods may provide clinical benefits for the …

[HTML][HTML] A consensus conference to define the utility of advanced infectious disease diagnostics in solid organ transplant recipients

MM Azar, S Turbett, D Gaston, M Gitman… - American Journal of …, 2022 - Elsevier
The last decade has seen an explosion of advanced assays for the diagnosis of infectious
diseases, yet evidence-based recommendations to inform their optimal use in the care of …

Evaluation of three rapid diagnostic methods for direct identification of microorganisms in positive blood cultures

RM Martinez, ER Bauerle, FC Fang… - Journal of clinical …, 2014 - Am Soc Microbiol
The identification of organisms from positive blood cultures generally takes several days.
However, recently developed rapid diagnostic methods offer the potential for organism …

Advances in rapid molecular blood culture diagnostics: healthcare impact, laboratory implications, and multiplex technologies

RC She, JM Bender - The journal of applied laboratory medicine, 2019 - academic.oup.com
Background For far too long, the diagnosis of bloodstream infections has relied on time-
consuming blood cultures coupled with traditional organism identification and susceptibility …

Antibiotic cycling and antibiotic mixing: which one best mitigates antibiotic resistance?

RE Beardmore, R Peña-Miller, F Gori… - Molecular biology and …, 2017 - academic.oup.com
Can we exploit our burgeoning understanding of molecular evolution to slow the progress of
drug resistance? One role of an infection clinician is exactly that: to foresee trajectories to …

Performance evaluation of the Verigene®(Nanosphere) and FilmArray®(BioFire®) molecular assays for identification of causative organisms in bacterial bloodstream …

C Ward, K Stocker, J Begum, P Wade… - European Journal of …, 2015 - Springer
Molecular assays designed to provide bacterial identification and detection of resistance
genes directly from positive blood cultures can significantly reduce the time to definitive …

Evaluation of FilmArray and Verigene systems for rapid identification of positive blood cultures

MM Bhatti, S Boonlayangoor, KG Beavis… - Journal of clinical …, 2014 - Am Soc Microbiol
ABSTRACT The Verigene tests for Gram-positive and Gram-negative organisms in blood
culture and the FilmArray blood culture identification panel were assessed for their ability to …

Potential impact of a microarray-based nucleic acid assay for rapid detection of Gram-negative bacteria and resistance markers in positive blood cultures

N Mancini, L Infurnari, N Ghidoli… - Journal of clinical …, 2014 - Am Soc Microbiol
ABSTRACT We evaluated the Verigene Gram-negative blood culture (BC-GN) test, a
microarray that detects Gram-negative bacteria and several resistance genes. A total of 102 …