Surveying gut microbiome research in Africans: toward improved diversity and representation

R Brewster, FB Tamburini, E Asiimwe, O Oduaran… - Trends in …, 2019 - cell.com
Descriptive and translational investigations into the human gut microbiome (GM) are rapidly
expanding; however, studies are largely restricted to industrialized populations in the USA …

Repositioning of non-antibiotic drugs as an alternative to microbial resistance: a systematic review

VS Foletto, TF da Rosa, MB Serafin, A Bottega… - International Journal of …, 2021 - Elsevier
The global spread of microbial resistance coupled with high costs and slow pace in the
discovery of a new antibiotic have made drug repositioning an attractive and promising …

Association between gut microbiota and CD4 recovery in HIV-1 infected patients

W Lu, Y Feng, F Jing, Y Han, N Lyu, F Liu, J Li… - Frontiers in …, 2018 - frontiersin.org
Composition of the gut microbiota has been linked with human immunedeficiency virus (HIV)-
infected patients on antiretroviral therapy (ART). Evidence suggests that ART-treated …

Bacteria exposed to antiviral drugs develop antibiotic cross-resistance and unique resistance profiles

VJ Wallace, EG Sakowski, SP Preheim… - Communications …, 2023 - nature.com
Antiviral drugs are used globally as treatment and prophylaxis for long-term and acute viral
infections. Even though antivirals also have been shown to have off-target effects on …

Impact of antiretroviral drugs on the microbiome: unknown answers to important questions

S Pinto-Cardoso, NR Klatt… - Current Opinion in HIV …, 2018 - journals.lww.com
There are still many unanswered questions regarding ARVs and the gut microbiome. It is,
therefore, critical for researchers to address the effect of distinct ARV drugs on the …

Long-term suppressive cART is not sufficient to restore intestinal permeability and gut microbiota compositional changes

G Ancona, E Merlini, C Tincati, A Barassi… - Frontiers in …, 2021 - frontiersin.org
Background: We explored the long-term effects of cART on markers of gut damage,
microbial translocation, and paired gut/blood microbiota composition, with a focus on the …

Altered gut microbiome under antiretroviral therapy: Impact of efavirenz and zidovudine

S Ray, A Narayanan, CG Giske, U Neogi… - ACS infectious …, 2020 - ACS Publications
Millions of individuals currently living with HIV globally are receiving antiretroviral therapy
(ART) that suppresses viral replication and improves host immune responses. The …

Changes in intestinal microbiota in HIV-1-infected subjects following cART initiation: influence of CD4+ T cell count

Y Ji, F Zhang, R Zhang, Y Shen, L Liu… - Emerging microbes & …, 2018 - Taylor & Francis
The roles of immunodeficiency and combined antiretroviral therapy (cART) in shaping the
gut microbiota in HIV-1-infected subjects (HISs) have not been described thoroughly by time …

[HTML][HTML] Untangling the role of the microbiome across the stages of HIV disease

AM Ortiz, JM Brenchley - Current Opinion in HIV and AIDS, 2024 - journals.lww.com
Previous studies considering the role of the microbiome in people living with HIV largely
described viral acquisition as an intrusion on the host: microbiome interface. Re-framing this …

In vitro antibacterial activity of antiretroviral drugs on key commensal bacteria from the human microbiota

E Rubio-Garcia, N Ferrando, N Martin… - Frontiers in Cellular …, 2024 - frontiersin.org
Introduction Antiretroviral therapy has improved life expectancy in HIV-infected patients.
However, people living with HIV under antiretroviral therapy are at higher risks of developing …