Glaucomatous optic neuropathy is the leading cause of irreversible blindness in the world.
The chronic disease is characterized by optic nerve degeneration and vision field loss. The …

Purpose: To evaluate the effect of scleral crosslinking (SXL) on slowing experimental
progressive myopia in tree shrew eyes using sub-Tenon's injections of genipin (GEN) at …

Purpose: To determine whether genipin (a natural crosslinker) could reduce the colonization
and proliferation of bacteria and fungi in an ex vivo model of corneal infection. Methods: This …

The central vision-threatening event in glaucoma is dysfunction and loss of retinal ganglion
cells (RGCs), thought to be promoted by local tissue deformations. Here, we sought to …

It is widely accepted that biomechanics plays an important role in glaucoma
pathophysiology, but the mechanisms involved are largely unknown. Rats are a common …

Scleral crosslinking using genipin has been identified as a promising treatment approach for
myopia control. The efficacy of genipin to alter biomechanical properties of the sclera has …

Glaucoma is the leading cause of irreversible blindness and is characterized by the death of
retinal ganglion cells, which carry vision information from the retina to the brain. Although it …

Infectious keratitis is a vision-threatening microbial infection. The increasing antimicrobial
resistance and the fact that severe cases often evolve into corneal perforation necessitate …

Purpose: Genipin has been proposed as a possible neuroprotective therapy in myopia and
glaucoma. Here, we aim to determine the effects of prolonged genipin-induced scleral …

Purpose: A reference atlas of optic nerve (ON) retinal ganglion cell (RGC) axons could
facilitate studies of neuro-ophthalmic diseases by detecting subtle RGC axonal changes …