[HTML][HTML] piRNAs can trigger a multigenerational epigenetic memory in the germline of C. elegans
A Ashe, A Sapetschnig, EM Weick, J Mitchell… - Cell, 2012 - cell.com
Transgenerational effects have wide-ranging implications for human health, biological
adaptation, and evolution; however, their mechanisms and biology remain poorly …
adaptation, and evolution; however, their mechanisms and biology remain poorly …
The Caenorhabiditis elegans model as a reliable tool in neurotoxicology
Caenorhabiditis elegans (C. elegans) offers an attractive experimental platform as it has a
short life cycle, is inexpensive to maintain and most importantly has high degree of …
short life cycle, is inexpensive to maintain and most importantly has high degree of …
Utility of Caenorhabditis elegans in high throughput neurotoxicological research
Caenorhabditis elegans is a nematode that has been used as a valuable research tool in
many facets of biological research. Researchers have used the many tools available to …
many facets of biological research. Researchers have used the many tools available to …
[HTML][HTML] Lysosome-related organelles in intestinal cells are a zinc storage site in C. elegans
Zinc is an essential trace element involved in many biological processes and human
diseases. Because zinc deficiency and excess are deleterious, animals require homeostatic …
diseases. Because zinc deficiency and excess are deleterious, animals require homeostatic …
Orsay Virus infection of Caenorhabditis elegans is modulated by zinc and dependent on lipids
LA Casorla-Perez, R Guennoun, C Cubillas… - Journal of …, 2022 - Am Soc Microbiol
Viruses utilize host lipids to promote the viral life cycle, but much remains unknown as to
how this is regulated. Zinc is a critical element for life, and few studies have linked zinc to …
how this is regulated. Zinc is a critical element for life, and few studies have linked zinc to …
[HTML][HTML] Zinc Levels Modulate Lifespan through Multiple Longevity Pathways in Caenorhabditis elegans
J Kumar, T Barhydt, A Awasthi, GJ Lithgow… - PLoS …, 2016 - journals.plos.org
Zinc is an essential trace metal that has integral roles in numerous biological processes,
including enzymatic function, protein structure, and cell signaling pathways. Both excess …
including enzymatic function, protein structure, and cell signaling pathways. Both excess …
[HTML][HTML] Natural variation in the sequestosome-related gene, sqst-5, underlies zinc homeostasis in Caenorhabditis elegans
Zinc is an essential trace element that acts as a co-factor for many enzymes and
transcription factors required for cellular growth and development. Altering intracellular zinc …
transcription factors required for cellular growth and development. Altering intracellular zinc …
Characterization of the effects of methylmercury on Caenorhabditis elegans
KJ Helmcke, T Syversen, DM Miller III… - Toxicology and applied …, 2009 - Elsevier
The rising prevalence of methylmercury (MeHg) in seafood and in the global environment
provides an impetus for delineating the mechanism of the toxicity of MeHg. Deleterious …
provides an impetus for delineating the mechanism of the toxicity of MeHg. Deleterious …
The Glutaredoxin GLRX-21 Functions to Prevent Selenium-Induced Oxidative Stress in Caenorhabditis elegans
KL Morgan, AO Estevez, CL Mueller… - Toxicological …, 2010 - academic.oup.com
Selenium is an essential micronutrient that functions as an antioxidant. Yet, at higher
concentrations, selenium is pro-oxidant and toxic. In extreme cases, exposures to excess …
concentrations, selenium is pro-oxidant and toxic. In extreme cases, exposures to excess …
[HTML][HTML] Histidine Protects Against Zinc and Nickel Toxicity in Caenorhabditis elegans
JT Murphy, JJ Bruinsma, DL Schneider, S Collier… - PLoS …, 2011 - journals.plos.org
Zinc is an essential trace element involved in a wide range of biological processes and
human diseases. Zinc excess is deleterious, and animals require mechanisms to protect …
human diseases. Zinc excess is deleterious, and animals require mechanisms to protect …