The trend of growth and aging of population worldwide will pose new challenges in health
care, which will require faster solutions addressed to specific pacient needs. In this regard …

Background Jaw-bone defects caused by various diseases lead to aesthetic and functional
complications, which can seriously affect the life quality of patients. Current treatments …

Craniofacial bone defects are one of the biggest clinical challenges in regenerative
medicine, with secondary autologous bone grafting being the gold-standard technique. The …

Reconstruction of critical-size bone defects (CSDs) in the craniomaxillofacial (CMF) region
remains challenging. Scaffold-based bone-engineered constructs have been proposed as …

Craniofacial development comprises a complex process in humans in which failures or
disturbances frequently lead to congenital anomalies. Cleft lip with/without palate (CL/P) is a …

The repair of alveolar bone defects is one of the urgent clinical problems to be solved.
Injectable microcarriers show great potential for bone repair due to their ability to fill irregular …

This study aimed to evaluate the effectiveness of autologous platelet derivatives (APD),
specifically platelet-rich plasma (PRP) or platelet-rich fibrin (PRF), combined with …

Background Alveolar cleft grafting is a necessary procedure to restore bone defects.
Randomized clinical trials (RCTs) are regarded as a golden standard for investigating the …

Objective The aim of the present study was to investigate the influence of three grafting
materials for cleft repair on orthodontic tooth movement in rats. Materials and methods …

To minimize the postoperative risks posed by grafting autologous transplants for cleft repair,
efforts are being made to improve grafting materials for use as potential alternatives. The …