Oxycodone in the opioid epidemic: high 'liking','wanting', and abuse liability
It is estimated that nearly a third of people who abuse drugs started with prescription opioid
medicines. Approximately, 11.5 million Americans used prescription drugs recreationally in …
medicines. Approximately, 11.5 million Americans used prescription drugs recreationally in …
An overview of recent developments in the management of burn injuries
E Radzikowska-Büchner, I Łopuszyńska… - International journal of …, 2023 - mdpi.com
According to the World Health Organization (WHO), around 11 million people suffer from
burns every year, and 180,000 die from them. A burn is a condition in which heat, chemical …
burns every year, and 180,000 die from them. A burn is a condition in which heat, chemical …
Oral oxycodone self‐administration leads to features of opioid misuse in male and female mice
Use of prescription opioids, particularly oxycodone, is an initiating factor driving the current
opioid epidemic. There are several challenges with modelling oxycodone abuse. First …
opioid epidemic. There are several challenges with modelling oxycodone abuse. First …
Endogenous opioids at the intersection of opioid addiction, pain, and depression: the search for a precision medicine approach
Opioid addiction and overdose are at record levels in the United States. This is driven, in
part, by their widespread prescription for the treatment of pain, which also increased …
part, by their widespread prescription for the treatment of pain, which also increased …
Oxycodone, an opioid like the others?
N Marie, F Noble - Frontiers in Psychiatry, 2023 - frontiersin.org
The over-prescription of opioid analgesics is a growing problem in the field of addiction,
which has reached epidemic-like proportions in North America. Over the past decade …
which has reached epidemic-like proportions in North America. Over the past decade …
Opioid addiction: who are your real friends?
Opioid addiction is a chronic and relapsing mental health disorder. However, only some
individuals exposed to opioids, either recreationally or during the course of pain …
individuals exposed to opioids, either recreationally or during the course of pain …
[PDF][PDF] Genetic addiction risk score (GARS)™, a predictor of vulnerability to opioid dependence
175 1. ABSTRACT Genetic addiction risk score (GARS) ™, a predictor of vulnerability to opioid
dependence Kenneth Blum1-8,10,18 Page 1 175 1. ABSTRACT The interaction of …
dependence Kenneth Blum1-8,10,18 Page 1 175 1. ABSTRACT The interaction of …
Drug-specific differences in the ability of opioids to manage burn pain
MA Emery, S Eitan - Burns, 2020 - Elsevier
Burn injury pain is a significant public health problem. Burn injury treatment has improved
tremendously in recent decades. However, an unintended consequence is that a larger …
tremendously in recent decades. However, an unintended consequence is that a larger …
Members of the same pharmacological family are not alike: Different opioids, different consequences, hope for the opioid crisis?
MA Emery, S Eitan - Progress in Neuro-Psychopharmacology and …, 2019 - Elsevier
Pain management is the specialized medical practice of modulating pain perception and
thus easing the suffering and improving the life quality of individuals suffering from painful …
thus easing the suffering and improving the life quality of individuals suffering from painful …
The roles of chemokine CXCL13 in the development of bone cancer pain and the regulation of morphine analgesia in rats
HL Bu, YZ Xia, PM Liu, HM Guo, C Yuan, XC Fan… - Neuroscience, 2019 - Elsevier
Chemokines are important regulators of immune, inflammatory, and neuronal responses in
peripheral and central pain pathway. The aim of this study was to investigate whether …
peripheral and central pain pathway. The aim of this study was to investigate whether …