A holistic review on Cryptococcus neoformans

SS Rathore, J Sathiyamoorthy, C Lalitha… - Microbial …, 2022 - Elsevier
Cryptococcus neoformans is an encapsulated fungal pathogen that causes infection in
immunocompromised individuals such as HIV patients, organ transplant patients …

Pulmonary cryptococcosis: a review of pathobiology and clinical aspects

F Setianingrum, R Rautemaa-Richardson… - Medical …, 2019 - academic.oup.com
Pulmonary cryptococcosis is an important opportunistic invasive mycosis in
immunocompromised patients, but it is also increasingly seen in immunocompetent patients …

Regulatory circuitry governing fungal development, drug resistance, and disease

RS Shapiro, N Robbins, LE Cowen - Microbiology and molecular …, 2011 - Am Soc Microbiol
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …

Mechanisms of fungal dissemination

AB Strickland, M Shi - Cellular and Molecular Life Sciences, 2021 - Springer
Fungal infections are an increasing threat to global public health. There are more than six
million fungal species worldwide, but less than 1% are known to infect humans. Most of …

[HTML][HTML] Cryptococcus neoformans Infection in the Central Nervous System: The Battle between Host and Pathogen

Y Chen, ZW Shi, AB Strickland, M Shi - Journal of Fungi, 2022 - mdpi.com
Cryptococcus neoformans (C. neoformans) is a pathogenic fungus with a global distribution.
Humans become infected by inhaling the fungus from the environment, and the fungus …

Innate antifungal immunity: the key role of phagocytes

GD Brown - Annual review of immunology, 2011 - annualreviews.org
Fungal diseases have emerged as significant causes of morbidity and mortality, particularly
in immune-compromised individuals, prompting greater interest in understanding the …

Expanding fungal pathogenesis: Cryptococcus breaks out of the opportunistic box

JW Kronstad, R Attarian, B Cadieux, J Choi… - Nature reviews …, 2011 - nature.com
Cryptococcus neoformans is generally considered to be an opportunistic fungal pathogen
because of its tendency to infect immunocompromised individuals, particularly those …

[HTML][HTML] Pattern recognition receptors in antifungal immunity

A Plato, SE Hardison, GD Brown - Seminars in immunopathology, 2015 - Springer
Receptors of the innate immune system are the first line of defence against infection, being
able to recognise and initiate an inflammatory response to invading microorganisms. The …

Molecular mechanisms of cryptococcal meningitis

TB Liu, DS Perlin, C Xue - Virulence, 2012 - Taylor & Francis
Fungal meningitis is a serious disease caused by a fungal infection of the central nervous
system (CNS) mostly in individuals with immune system deficiencies. Fungal meningitis is …

The primary target organ of Cryptococcus gattii is different from that of Cryptococcus neoformans in a murine model

P Ngamskulrungroj, Y Chang, E Sionov… - MBio, 2012 - Am Soc Microbiol
Cryptococcosis is caused by the opportunistic pathogen Cryptococcus neoformans or by the
primary pathogen Cryptococcus gattii. Epidemiological studies suggest that patients infected …