The immune and endocrine dysfunctions of white adipose tissue are a hallmark of metabolic
disorders such as obesity and type 2 diabetes. In humans, white adipose tissue comprises …

Preclinical models are essential research tools before novel therapeutic or diagnostic
methods can be applied to humans. These range from in vitro cell monocultures to vastly …

Background Despite their heterogeneity, the current standard preoperative radiotherapy
regimen for localized high-grade soft tissue sarcoma (STS) follows a one fits all approach for …

With obesity and its comorbidities continuing to rise, we urgently need to improve our
understanding of what mechanisms trigger the white adipose tissue to become dysfunctional …

In bone tissue engineering (TE) and regeneration, miniaturized,(sub) millimeter-sized bone
models have become a popular trend since they bring about physiological biomimicry …

Obesity, a burgeoning global health crisis, has tripled in prevalence over the past 45 years,
necessitating innovative research methodologies. Adipocytes, which are responsible for …

Obesity-related metabolic diseases, including obesity, diabetes, hyperlipidemia, and non-
alcoholic fatty liver diseases pose a significant threat to health. However, comprehensive …

We present a protocol that describes the properties and advantages of using a standalone
clinostat incubator for growing, treating, and monitoring 3D cell cultures. The clinostat …

The utilization of thin plate systems based on acoustic vibration holds significant importance
in micro-nano manipulation and the exploration of nonlinear science. This paper focuses on …

Not long ago, researchers were skeptical of the value of culturing cells in a 3D environment.
Today, 3D cell culture has become a routine tool that plays a vital role in drug discovery and …