Pathogenesis and therapeutic mechanisms in immune thrombocytopenia (ITP)
Immune thrombocytopenia (ITP) is a complex autoimmune disease characterized by low
platelet counts. The pathogenesis of ITP remains unclear although both antibody-mediated …
platelet counts. The pathogenesis of ITP remains unclear although both antibody-mediated …
Pathogenesis of immune thrombocytopenia
S Audia, M Mahévas, M Samson, B Godeau… - Autoimmunity …, 2017 - Elsevier
Immune thrombocytopenia (ITP) is a rare autoimmune disease due to an abnormal T cell
response, notably supported by splenic T follicular helper cells, that stimulates the …
response, notably supported by splenic T follicular helper cells, that stimulates the …
How we treat primary immune thrombocytopenia in adults
X Liu, Y Hou, M Hou - Journal of Hematology & Oncology, 2023 - Springer
Primary immune thrombocytopenia (ITP) is an immune-mediated bleeding disorder
characterized by decreased platelet counts and an increased risk of bleeding. Multiple …
characterized by decreased platelet counts and an increased risk of bleeding. Multiple …
Platelets and the immune continuum
JW Semple, JE Italiano, J Freedman - Nature Reviews Immunology, 2011 - nature.com
Platelets are anucleate cells that are crucial mediators of haemostasis. Most immunologists
probably don't think about platelets every day, and may even consider these cells to …
probably don't think about platelets every day, and may even consider these cells to …
Emerging concepts in immune thrombocytopenia
M Swinkels, M Rijkers, J Voorberg… - Frontiers in …, 2018 - frontiersin.org
Immune thrombocytopenia (ITP) is an autoimmune disease defined by low platelet counts
which presents with an increased bleeding risk. Several genetic risk factors (eg …
which presents with an increased bleeding risk. Several genetic risk factors (eg …
Role of platelets in detection and regulation of infection
I Portier, RA Campbell - Arteriosclerosis, thrombosis, and vascular …, 2021 - Am Heart Assoc
Platelets are classically known as essential mediators of hemostasis and thrombosis.
However, in recent years, platelets have gained recognition for their inflammatory functions …
However, in recent years, platelets have gained recognition for their inflammatory functions …
COVID-19 vaccines and autoimmune hematologic disorders
ME Mingot-Castellano, N Butta, M Canaro… - Vaccines, 2022 - mdpi.com
Worldwide vaccination against SARS-CoV-2 has allowed the detection of hematologic
autoimmune complications. Adverse events (AEs) of this nature had been previously …
autoimmune complications. Adverse events (AEs) of this nature had been previously …
Improved regulatory T-cell activity in patients with chronic immune thrombocytopenia treated with thrombopoietic agents
W Bao, JB Bussel, S Heck, W He… - Blood, The Journal …, 2010 - ashpublications.org
Immune thrombocytopenia (ITP) is an autoantibody-mediated bleeding disorder with both
accelerated platelet destruction and impaired platelet production. We and others have …
accelerated platelet destruction and impaired platelet production. We and others have …
Revisiting platelets and toll-like receptors (TLRs): at the interface of vascular immunity and thrombosis
K Hally, S Fauteux-Daniel… - International journal of …, 2020 - mdpi.com
While platelet function has traditionally been described in the context of maintaining
vascular integrity, recent evidence suggests that platelets can modulate inflammation in a …
vascular integrity, recent evidence suggests that platelets can modulate inflammation in a …
Crosstalk between platelets and microbial pathogens
Platelets, small anucleate cells circulating in the blood, are critical mediators in haemostasis
and thrombosis. Interestingly, recent studies demonstrated that platelets contain both pro …
and thrombosis. Interestingly, recent studies demonstrated that platelets contain both pro …