Objective: Cholesterol is an important molecule in humans and both its excess and its
deficiency cause disease. Most clinicians appreciate its role in stabilizing cellular plasma …

Aromatic hydrocarbons such as benzene and polycyclic aromatic hydrocarbons (PAHs) are
very slowly degraded without molecular oxygen. Here, we review the recent advances in the …

Tuberculosis is a distinctive disease in which the causative agent, Mycobacterium
tuberculosis, can persist in humans for decades by avoiding clearance from host immunity …

Steroid-based drugs have been developed as the second largest medical category in
pharmaceutics. The well-established route of steroid industry includes two steps: the …

Current tuberculosis (TB) drug development efforts are not sufficient to end the global TB
epidemic. Recent efforts have focused on the development of whole-cell screening assays …

Background: There are ever increasing researches implying that noncoded RNAs (ncRNAs)
specifically circular RNAs (circRNAs) and microRNAs (miRNAs) in exosomes play vital roles …

This study was conducted to investigate the role of iron deprivation in the persistence of
Mycobacterium tuberculosis. We present evidence of iron restriction in human necrotic …

Highlights•We highlight recent findings in M. tuberculosis lipid metabolism during
infection.•We describe mechanisms of host lipid accumulation during M. tuberculosis …

Steroids are ubiquitous in natural environments and are a significant growth substrate for
microorganisms. Microbial steroid metabolism is also important for some pathogens and for …

The generation of phagosomal cytotoxic reactive species (ie, free radicals and oxidants) by
activated macrophages and neutrophils is a crucial process for the control of intracellular …