Bioerodable PLGA-based microparticles for producing sustained-release drug formulations and strategies for improving drug loading

FY Han, KJ Thurecht, AK Whittaker… - Frontiers in …, 2016 - frontiersin.org
Poly (lactic-co-glycolic acid)(PLGA) is the most widely used biomaterial for
microencapsulation and prolonged delivery of therapeutic drugs, proteins and antigens …

Vitamin E TPGS as a molecular biomaterial for drug delivery

Z Zhang, S Tan, SS Feng - Biomaterials, 2012 - Elsevier
d-α-tocopheryl polyethylene glycol succinate (Vitamin E TPGS, or simply TPGS) is a water-
soluble derivative of natural Vitamin E, which is formed by esterification of Vitamin E …

Current advances in research and clinical applications of PLGA-based nanotechnology

JM Lü, X Wang, C Marin-Muller, H Wang… - Expert review of …, 2009 - Taylor & Francis
Co-polymer poly (lactic-co-glycolic acid)(PLGA) nanotechnology has been developed for
many years and has been approved by the US FDA for the use of drug delivery, diagnostics …

[HTML][HTML] Paclitaxel nano-delivery systems: a comprehensive review

P Ma, RJ Mumper - Journal of nanomedicine & nanotechnology, 2013 - ncbi.nlm.nih.gov
Paclitaxel is one of the most effective chemotherapeutic drugs ever developed and is active
against a broad range of cancers, such as lung, ovarian, and breast cancers. Due to its low …

Vitamin E TPGS-based nanomedicine, nanotheranostics, and targeted drug delivery: past, present, and future

AK Mehata, A Setia, AK Malik, R Hassani, HG Dailah… - Pharmaceutics, 2023 - mdpi.com
It has been seventy years since a water-soluble version of vitamin E called tocophersolan
(also known as TPGS) was produced; it was approved by USFDA in 1998 as an inactive …

Nanoscale drug delivery systems for cancer therapy using paclitaxel—A review of challenges and latest progressions

G Mustafa, D Hassan, G Ruiz-Pulido… - Journal of Drug Delivery …, 2023 - Elsevier
Paclitaxel (PTX) is an effective anticancer chemical with a broad spectrum that was primarily
obtained from a curative shrub, specifically the bark of Taxus brevifolia tree. It belongs to a …

A physical model for the size-dependent cellular uptake of nanoparticles modified with cationic surfactants

A Xu, M Yao, G Xu, J Ying, W Ma, B Li… - International journal of …, 2012 - Taylor & Francis
Background The aim of this work was to improve oral bioavailability. The uptake of a series
of quaternary ammonium salt didodecyl dimethylammonium bromide (DMAB)-modified …

Peptide-based hydrogel nanoparticles as effective drug delivery agents

R Ischakov, L Adler-Abramovich, L Buzhansky… - Bioorganic & medicinal …, 2013 - Elsevier
Peptide-based hydrogel nanoparticles represent a promising alternative to current drug
delivery approaches. We have previously demonstrated that the Fmoc-FF aromatic dipeptide …

[HTML][HTML] Combating atherosclerosis with targeted nanomedicines: recent advances and future prospective

A Nakhlband, M Eskandani, Y Omidi, N Saeedi… - BioImpacts …, 2018 - ncbi.nlm.nih.gov
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Introduction: Cardiovascular diseases (CVDs) is recognized as the leading cause of …

Combination of Paclitaxel and R-flurbiprofen loaded PLGA nanoparticles suppresses glioblastoma growth on systemic administration

S Caban-Toktas, A Sahin, S Lule, G Esendagli… - International Journal of …, 2020 - Elsevier
Malignant gliomas are highly lethal. Delivering chemotherapeutic drugs to the brain in
sufficient concentration is the major limitation in their treatment due to the blood-brain barrier …