[HTML][HTML] Quantitative molecular positron emission tomography imaging using advanced deep learning techniques

H Zaidi, I El Naqa - Annual review of biomedical engineering, 2021 - annualreviews.org
The widespread availability of high-performance computing and the popularity of artificial
intelligence (AI) with machine learning and deep learning (ML/DL) algorithms at the helm …

Microfluidic radiobioassays: a radiometric detection tool for understanding cellular physiology and pharmacokinetics

Z Liu, X Lan - Lab on a Chip, 2019 - pubs.rsc.org
The investigation of molecular uptake and its kinetics in cells is valuable for understanding
the cellular physiological status, the observation of drug interventions, and the development …

[HTML][HTML] Surgical radioguidance with beta-emitting radionuclides; challenges and possibilities: a position paper by the EANM

P Fragoso Costa, K Shi, S Holm, S Vidal-Sicart… - European journal of …, 2024 - Springer
Radioguidance that makes use of β-emitting radionuclides is gaining in popularity and could
have potential to strengthen the range of existing radioguidance techniques. While there is a …

A mini-panel PET scanner-based microfluidic radiobioassay system allowing high-throughput imaging of real-time cellular pharmacokinetics

Z Liu, P Zhang, H Ji, Y Long, B Jing, L Wan, D Xi, R An… - Lab on a Chip, 2020 - pubs.rsc.org
On-chip radiometric detection of biological samples using radiotracers has become an
emerging research field known as microfluidic radiobioassays. Performing parallel …

Overview of current applications of the Timepix detector in spectroscopy, radiation and medical physics

R Al Darwish, L Marcu, E Bezak - Applied Spectroscopy Reviews, 2020 - Taylor & Francis
With the current developments in medical physics and radiotherapy, there is a renewed
interest in novel microdosimetry detectors. The Timepix detector, developed at CERN as an …

Performance evaluation of 18F radioluminescence microscopy using computational simulation

Q Wang, D Sengupta, TJ Kim, G Pratx - Medical physics, 2017 - Wiley Online Library
Purpose Radioluminescence microscopy can visualize the distribution of beta‐emitting
radiotracers in live single cells with high resolution. Here, we perform a computational …

[HTML][HTML] Proof of concept of a multimodal intravital molecular imaging system for tumour transpathology investigation

Z Liu, T Cheng, S Düwel, Z Jian, GJ Topping… - European journal of …, 2021 - Springer
Background Transpathology highlights the interpretation of the underlying physiology
behind molecular imaging. However, it remains challenging due to the discrepancies …

In silico optimization of radioluminescence microscopy

Q Wang, D Sengupta, TJ Kim, G Pratx - Journal of biophotonics, 2018 - Wiley Online Library
Radioluminescence microscopy (RLM) is a high‐resolution method for imaging radionuclide
uptake in live cells within a fluorescence microscopy environment. Although RLM currently …

18F autoradiography With the Mimosa-28: Characterization and Application

TN Pham, P Marchand, C Finck… - … on Radiation and …, 2020 - ieeexplore.ieee.org
Autoradiography (AR) is a technique used to record the spatial distribution of a radiotracer
into an ex-vivo tissue slice. Within the section, the radioactive molecules emit charged …

High-resolution radioluminescence microscopy image reconstruction via ionization track analysis

S Almasi, G Pratx - … on Radiation and Plasma Medical Sciences, 2019 - ieeexplore.ieee.org
Radioluminescence microscopy (RLM) is a newly developed paradigm for visualizing
radiotracer uptake in live cells. High-resolution images are obtained by capturing the …