Addiction is driven by excessive goal-directed drug choice under negative affect: translational critique of habit and compulsion theory

L Hogarth - Neuropsychopharmacology, 2020 - nature.com
Drug addiction may be a goal-directed choice driven by excessive drug value in negative
affective states, a habit driven by strong stimulus− response associations, or a compulsion …

Habit, choice, and addiction

Y Vandaele, SH Ahmed - Neuropsychopharmacology, 2021 - nature.com
Addiction was suggested to emerge from the progressive dominance of habits over goal-
directed behaviors. However, it is generally assumed that habits do not persist in choice …

Habitual behavior is goal-driven

AW Kruglanski, E Szumowska - … on Psychological Science, 2020 - journals.sagepub.com
We address the relation between goal-driven and habitual behaviors. Whereas in recent
years the two have been juxtaposed, we suggest that habitual behavior is in fact goal-driven …

Behavioral and neural mechanisms underlying habitual and compulsive drug seeking

RJ Smith, LS Laiks - Progress in Neuro-Psychopharmacology and …, 2018 - Elsevier
Addiction is characterized by compulsive drug use despite negative consequences. Here we
review studies that indicate that compulsive drug use, and in particular punishment …

Intact goal‐directed control in treatment‐seeking drug users indexed by outcome‐devaluation and Pavlovian to instrumental transfer: critique of habit theory

L Hogarth, C Lam‐Cassettari, H Pacitti… - European Journal of …, 2019 - Wiley Online Library
Animal studies have demonstrated that chronic exposure to drugs of abuse impairs goal‐
directed control over action selection indexed by the outcome‐devaluation and specific …

Chronic methamphetamine self-administration disrupts cortical control of cognition

A Bernheim, RE See, CM Reichel - Neuroscience & Biobehavioral …, 2016 - Elsevier
Methamphetamine (meth) is one of the most abused substances worldwide. Chronic use
has been associated with repeated relapse episodes that may be exacerbated by cognitive …

A critical review of habit theory of drug dependence

L Hogarth - The psychology of habit: Theory, mechanisms, change …, 2018 - Springer
Animal behavioural research has shown that chronic drug exposure renders instrumental
behaviour prone to habitual as opposed to goal-directed control. It is claimed that the same …

The role of the basal ganglia in motivated behavior

C Da Cunha, A Gomez-A, CD Blaha - Reviews in the Neurosciences, 2012 - degruyter.com
The present paper reviews foundational and contemporary theories of motivated behaviors
and the growing body of evidence that they require specific functional interactions within the …

Individual decision-making in the causal pathway to addiction: contributions and limitations of rodent models

SH Ahmed - Pharmacology Biochemistry and Behavior, 2018 - Elsevier
The causal pathway from vulnerability to drug use and addiction involves a complex
interaction between genetic, environmental, and behavioral factors. An individual can …

Relative timing between kappa opioid receptor activation and cocaine determines the impact on reward and dopamine release

EH Chartoff, SR Ebner, A Sparrow, D Potter… - …, 2016 - nature.com
Negative affective states can increase the rewarding value of drugs of abuse and promote
drug taking. Chronic cocaine exposure increases levels of the neuropeptide dynorphin, an …