Astrovirus biology and pathogenesis

V Cortez, VA Meliopoulos, EA Karlsson… - Annual review of …, 2017 - annualreviews.org
Astroviruses are nonenveloped, positive-sense single-stranded RNA viruses that cause
gastrointestinal illness. Although a leading cause of pediatric diarrhea, human astroviruses …

A guide to utilization of the microbiology laboratory for diagnosis of infectious diseases: 2018 update by the Infectious Diseases Society of America and the American …

JM Miller, MJ Binnicker, S Campbell… - Clinical Infectious …, 2018 - academic.oup.com
The critical nature of the microbiology laboratory in infectious disease diagnosis calls for a
close, positive working relationship between the physician/advanced practice provider and …

Intra-and cross-species transmission of astroviruses

SN Roach, RA Langlois - Viruses, 2021 - mdpi.com
Astroviruses are non-enveloped, single-stranded RNA viruses that infect mammalian and
avian species. In humans, astrovirus infections are one of the most common causes of …

Targeted metagenomic sequencing for detection of vertebrate viruses in wastewater for public health surveillance

C McCall, RA Leo Elworth, KM Wylie, TN Wylie… - ACS ES&T …, 2023 - ACS Publications
Viruses of concern for quantitative wastewater monitoring are usually selected as a result of
an outbreak and subsequent detection in wastewater. In addition, targeted metagenomics …

An annoying enteric virus: A systematic review and meta‐analysis of human astroviruses and gastrointestinal complications in children

MH Razizadeh, K Pourrostami… - Reviews in Medical …, 2022 - Wiley Online Library
Human astroviruses (HAstVs) have frequently been detected in individuals with acute
gastroenteritis (AGE). However, a precise estimate of the overall prevalence of the virus in …

Molecular epidemiology of astrovirus in children with gastroenteritis in southwestern Nigeria

KO Arowolo, CI Ayolabi, IA Adeleye, B Lapinski… - Archives of …, 2020 - Springer
Human astrovirus (HAstV) is recognized as one of the major causative agents of acute
gastroenteritis in children worldwide. Data on the genetic diversity of HAstV in Nigeria are …

Isolation of neutralizing monoclonal antibodies to human astrovirus and characterization of virus variants that escape neutralization

R Espinosa, T López, WA Bogdanoff… - Journal of …, 2019 - Am Soc Microbiol
Human astroviruses (HAstVs) cause severe diarrhea and represent an important health
problem in children under two years of age. Despite their medical importance, the study of …

Characterizing a murine model for astrovirus using viral isolates from persistently infected immunocompromised mice

V Cortez, B Sharp, J Yao, B Livingston, P Vogel… - Journal of …, 2019 - Am Soc Microbiol
Human astroviruses are single-stranded RNA enteric viruses that cause a spectrum of
disease ranging from asymptomatic infection to systemic extragastrointestinal spread; …

Epidemiology of human astroviruses among children younger than 5 years: prospective hospital‐based sentinel surveillance in South Africa, 2009‐2014

S Nadan, MB Taylor, MJ Groome… - Journal of Medical …, 2019 - Wiley Online Library
Background The epidemiology of human astroviruses (HAstVs) in hospitalised patients less
than 5 years of age from selected sites in South Africa was investigated. Diarrheagenic stool …

Structures of two human astrovirus capsid/neutralizing antibody complexes reveal distinct epitopes and inhibition of virus attachment to cells

L Ricemeyer, N Aguilar-Hernández, T López… - Journal of …, 2022 - Am Soc Microbiol
Human astrovirus is an important cause of viral gastroenteritis worldwide. Young children,
the elderly, and the immunocompromised are especially at risk for contracting severe …