The role of cytochrome P450s in insect toxicology and resistance

R Nauen, C Bass, R Feyereisen… - Annual Review of …, 2022 - annualreviews.org
Insect cytochrome P450 monooxygenases (P450s) perform a variety of important
physiological functions, but it is their role in the detoxification of xenobiotics, such as natural …

The role of cytochrome P450-mediated detoxification in insect adaptation to xenobiotics

K Lu, Y Song, R Zeng - Current Opinion in Insect Science, 2021 - Elsevier
Insect cytochrome P450 monooxygenases (P450s) are well known to be involved in
metabolic detoxification of xenobiotics, such as phytochemicals, insecticides and …

Management of insecticide resistance in the major Aedes vectors of arboviruses: Advances and challenges

I Dusfour, J Vontas, JP David, D Weetman… - PLoS neglected …, 2019 - journals.plos.org
Background The landscape of mosquito-borne disease risk has changed dramatically in
recent decades, due to the emergence and reemergence of urban transmission cycles …

Insect CYP genes and P450 enzymes

R Feyereisen - Insect molecular biology and biochemistry, 2012 - Elsevier
Publisher Summary This chapter discusses the insect CYP genes and P450 enzymes.
Cytochrome P450, or CYP genes, constitutes one of the largest family of genes, with …

Contribution of insect gut microbiota and their associated enzymes in insect physiology and biodegradation of pesticides

S Jaffar, S Ahmad, Y Lu - Frontiers in Microbiology, 2022 - frontiersin.org
Synthetic pesticides are extensively and injudiciously applied to control agriculture and
household pests worldwide. Due to their high use, their toxic residues have enormously …

Sublethal exposure, insecticide resistance, and community stress

RNC Guedes, SS Walse, JE Throne - Current opinion in insect science, 2017 - Elsevier
Highlights•Sublethal stress remains neglected within entomology in favor of short-term
mortality.•Sublethal stress in insecticide-resistant populations and insect communities is also …

[HTML][HTML] Impact of environment on mosquito response to pyrethroid insecticides: facts, evidences and prospects

TE Nkya, I Akhouayri, W Kisinza, JP David - Insect biochemistry and …, 2013 - Elsevier
By transmitting major human diseases such as malaria, dengue fever and filariasis,
mosquito species represent a serious threat worldwide in terms of public health, and pose a …

Role of cytochrome P450s in insecticide resistance: impact on the control of mosquito-borne diseases and use of insecticides on Earth

JP David, HM Ismail… - … Transactions of the …, 2013 - royalsocietypublishing.org
The fight against diseases spread by mosquitoes and other insects has enormous
environmental, economic and social consequences. Chemical insecticides remain the first …

The classification of esterases: an important gene family involved in insecticide resistance-A review

IR Montella, R Schama, D Valle - Memorias do Instituto Oswaldo Cruz, 2012 - SciELO Brasil
The use of chemical insecticides continues to play a major role in the control of disease
vector populations, which is leading to the global dissemination of insecticide resistance. A …

Cytochrome P450s–Their expression, regulation, and role in insecticide resistance

N Liu, M Li, Y Gong, F Liu, T Li - Pesticide biochemistry and physiology, 2015 - Elsevier
P450s are known to be critical for the detoxification and/or activation of xenobiotics such as
drugs and pesticides and overexpression of P450 genes can significantly affect the …