Dried blood spots (DBS) typically consist in the deposition of small volumes of capillary
blood onto dedicated paper cards. Comparatively to whole blood or plasma samples, their …

Methods to measure metabolites of steroid hormones from faeces have become very
popular in wildlife conservation and ecology, because they allow gathering physiological …

A frequently debated question for studies involving the measurement of stress hormones in
rodents is the optimal method for collecting blood with minimal stress to the animal. Some …

10+ Years of Updates Since First EditionNewcomers to the animal clinical chemistry and
toxicology fields quickly find that the same rules of human medicine do not always apply …

The circadian glucocorticoid rhythm provides important information on the functioning of the
hypothalamic-pituitary-adrenal axis in individuals. Frequent repeated blood sampling can …

Back-translating the clinical manifestations of human disease burden into animal models is
increasingly recognized as an important facet of preclinical drug discovery. We …

Rats are widely used in biomedical research as animal models for human diseases.
However, due to their small body size, blood sampling is complicated and invasive and …

Six 8‐week‐old Sprague‐Dawley rats were studied for 9 days divided into three periods of 3
days each: before transferral to metabolism cages, during metabolic cage housing and after …

This study was conducted to confirm our previous reports that group housing lowered basal
heart rate and various evoked heart-rate responses in Sprague–Dawley male and female …

Fasting is a common procedure for animals in experiments. Although fasting may be
necessary for scientific reasons, it should be minimized. In the current study, jugular …