Uterine fibroids: current perspectives

AT Khan, M Shehmar, JK Gupta - International journal of women's …, 2014 - Taylor & Francis
Uterine fibroids are a major cause of morbidity in women of a reproductive age (and
sometimes even after menopause). There are several factors that are attributed to underlie …

Systematic review of pregnancy outcomes after fertility-preserving treatment of uterine fibroids

SC Khaw, RA Anderson, M Lui - Reproductive biomedicine online, 2020 - Elsevier
The aim of this study was to compare pregnancy outcomes after medical (ulipristal acetate
[UPA]), surgical (myomectomy) and radiological (uterine artery embolization [UAE] or …

Reproductive impact of MRI-guided focused ultrasound surgery for fibroids: a systematic review of the evidence

NA Clark, SL Mumford, JH Segars - Current Opinion in Obstetrics …, 2014 - journals.lww.com
MRgFUS represents a minimally invasive treatment for uterine fibroids that is able to
improve the quality of life and fibroid size with durability. It is possible that MRgFUS could be …

High-intensity focused ultrasound ablation of uterine fibroids–potential impact on fertility and pregnancy outcome

MK Bohlmann, F Hoellen, P Hunold… - Geburtshilfe und …, 2014 - thieme-connect.com
Laparoscopic myomectomy is regarded as the gold standard for women with symptomatic
fibroids who wish to become pregnant. High-intensity focused ultrasound (HIFU or MRgFUS) …

Magnetic resonance imaging–guided focused ultrasound treatment of symptomatic uterine fibroids: impact of technology advancement on ablation volumes in 115 …

CG Trumm, R Stahl, DA Clevert, P Herzog… - Investigative …, 2013 - journals.lww.com
Objectives The aim of this study was to assess the impact of the advanced technology of the
new ExAblate 2100 system (Insightec Ltd, Haifa, Israel) for magnetic resonance imaging …

Laparoscopic myomectomy: clinical outcomes and comparative evidence

VA Buckley, EM Nesbitt-Hawes, P Atkinson… - Journal of Minimally …, 2015 - Elsevier
Laparoscopic myomectomy is a common surgical treatment for symptomatic uterine
leiomyomas. Proponents of the laparoscopic approach to myomectomy propose that the …

Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19

MJ Park, H Shen, JM Spaeth, JH Tolvanen… - Journal of Biological …, 2018 - ASBMB
Somatic mutations in exon 2 of the RNA polymerase II transcriptional Mediator subunit
MED12 occur at high frequency in uterine fibroids (UFs) and breast fibroepithelial tumors as …

Hysterectomy in Denmark 1977–2011: changes in rate, indications, and hospitalization

R Lykke, J Blaakær, B Ottesen, H Gimbel - European Journal of Obstetrics & …, 2013 - Elsevier
Objective To describe conditions regarding hysterectomy for benign indications during the
past 35 years in Denmark. Study design Population-based register study of 167,802 women …

Surgical methods for the treatment of uterine fibroids–risk of uterine sarcoma and problems of morcellation: position paper of the DGGG

MW Beckmann, I Juhasz-Böss… - Geburtshilfe und …, 2015 - thieme-connect.com
The appropriate surgical technique to treat patients with uterine fibroids is still a matter of
debate as is the potential risk of incorrect treatment if histological examination detects a …

A study of thermal dose-induced autophagy, apoptosis and necroptosis in colon cancer cells

PXE Mouratidis, I Rivens, G Ter Haar - International Journal of …, 2015 - Taylor & Francis
Purpose: The pleiotropic effects of heat on cancer cells have been well documented. The
biological effects seen depend on the temperature applied, and the heating duration. In this …