Effective use of nanocarriers as drug delivery systems for the treatment of selected tumors

FU Din, W Aman, I Ullah, OS Qureshi… - International journal …, 2017 - Taylor & Francis
Nanotechnology has recently gained increased attention for its capability to effectively
diagnose and treat various tumors. Nanocarriers have been used to circumvent the …

Calcium phosphate bioceramics: a review of their history, structure, properties, coating technologies and biomedical applications

N Eliaz, N Metoki - Materials, 2017 - mdpi.com
Calcium phosphate (CaP) bioceramics are widely used in the field of bone regeneration,
both in orthopedics and in dentistry, due to their good biocompatibility, osseointegration and …

[HTML][HTML] The role of tumor-associated macrophages (TAMs) in tumor progression and relevant advance in targeted therapy

Q Yang, N Guo, Y Zhou, J Chen, Q Wei… - Acta Pharmaceutica Sinica …, 2020 - Elsevier
Macrophages have a leading position in the tumor microenvironment (TME) which paves the
way to carcinogenesis. Initially, monocytes and macrophages are recruited to the sites …

Multifaceted role of the urokinase-type plasminogen activator (uPA) and its receptor (uPAR): diagnostic, prognostic, and therapeutic applications

N Mahmood, C Mihalcioiu, SA Rabbani - Frontiers in oncology, 2018 - frontiersin.org
The plasminogen activator (PA) system is an extracellular proteolytic enzyme system
associated with various physiological and pathophysiological processes. A large body of …

What blocks more anticancer platinum complexes from experiment to clinic: Major problems and potential strategies from drug design perspectives

K Peng, BB Liang, W Liu, ZW Mao - Coordination Chemistry Reviews, 2021 - Elsevier
Encouraged by the worldwide success of cisplatin in the field of cancer chemotherapy,
intensive works have been conducted to explore more platinum coordination complexes as …

[HTML][HTML] Recent advances in carrier mediated nose-to-brain delivery of pharmaceutics

V Bourganis, O Kammona, A Alexopoulos… - European Journal of …, 2018 - Elsevier
Central nervous system (CNS) disorders (eg, multiple sclerosis, Alzheimer's disease, etc.)
represent a growing public health issue, primarily due to the increased life expectancy and …

Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: a review

S Bose, S Tarafder - Acta biomaterialia, 2012 - Elsevier
Calcium phosphates (CaPs) are the most widely used bone substitutes in bone tissue
engineering due to their compositional similarities to bone mineral and excellent …

Bioengineered bacterial outer membrane vesicles as cell-specific drug-delivery vehicles for cancer therapy

V Gujrati, S Kim, SH Kim, JJ Min, HE Choy, SC Kim… - ACS …, 2014 - ACS Publications
Advances in genetic engineering tools have contributed to the development of strategies for
utilizing biologically derived vesicles as nanomedicines for achieving cell-specific drug …

Nanoparticles-based drug delivery and gene therapy for breast cancer: Recent advancements and future challenges

Z Mirza, S Karim - Seminars in cancer biology, 2021 - Elsevier
Breast cancer (BC) is amongst the most lethal cancer among females and conventional
treatment methods like surgery, radiotherapy and chemotherapy are not effective enough as …

Factors controlling nanoparticle pharmacokinetics: an integrated analysis and perspective

SM Moghimi, AC Hunter… - Annual review of …, 2012 - annualreviews.org
Intravenously injected nanoparticulate drug carriers provide a wide range of unique
opportunities for site-specific targeting of therapeutic agents to many areas within the …