STAT6: a review of a signaling pathway implicated in various diseases with a special emphasis in its usefulness in pathology

G Karpathiou, A Papoudou-Bai, E Ferrand… - … -Research and Practice, 2021 - Elsevier
Abstract Signal Transducer and Activator of Transcription 6 (STAT6), belonging to a family of
seven similar members is primarily stimulated by interleukin (IL)-4 and IL-13, and acts as a T …

Diagnostic challenges in meningioma

M Nowosielski, N Galldiks, S Iglseder… - Neuro …, 2017 - academic.oup.com
Advances in molecular profiling and the application of advanced imaging techniques are
currently refreshing diagnostic considerations in meningioma patients. Not only technical …

Extensive survey of STAT6 expression in a large series of mesenchymal tumors

EG Demicco, PW Harms, RM Patel… - American journal of …, 2015 - academic.oup.com
Objectives: Expression of strong nuclear STAT6 is thought to be a specific marker for solitary
fibrous tumors (SFTs). Little is known about subtle expression patterns in other …

Methylation-based classification of benign and malignant peripheral nerve sheath tumors

M Röhrich, C Koelsche, D Schrimpf, D Capper… - Acta …, 2016 - Springer
The vast majority of peripheral nerve sheath tumors derive from the Schwann cell lineage
and comprise diverse histological entities ranging from benign schwannomas and …

Novel therapeutic options for solitary fibrous tumor: antiangiogenic therapy and beyond

A de Bernardi, A Dufresne, F Mishellany, JY Blay… - Cancers, 2022 - mdpi.com
Simple Summary In the latest WHO classification, solitary fibrous tumors (SFTs) are now
subdivided into benign SFT (intermediate category (locally aggressive)), SFT NOS …

Distinct clinicopathological features of NAB2-STAT6 fusion gene variants in solitary fibrous tumor with emphasis on the acquisition of highly malignant potential

K Akaike, A Kurisaki-Arakawa, K Hara, Y Suehara… - Human pathology, 2015 - Elsevier
The impact of NGFI-A binding protein 2 (NAB2)-signal transducer and activator of
transcription 6 (STAT6) fusion on the biological behavior and the mechanism of acquisition …

Immunohistochemical approach to the differential diagnosis of meningiomas and their mimics

C Boulagnon-Rombi, C Fleury, C Fichel… - … of Neuropatholgy & …, 2017 - academic.oup.com
The differential diagnosis between meningioma and others tumors can be challenging. This
study aimed to evaluate different immunohistochemical markers for the differential diagnosis …

Molecular changes in solitary fibrous tumor progression

HK Park, DB Yu, M Sung, E Oh, M Kim, JY Song… - Journal of Molecular …, 2019 - Springer
Solitary fibrous tumors (SFTs) are NAB2-STAT6 fusion-associated neoplasms. There are
several subtypes of NAB2-STAT6 fusions, but their clinical significances are still unclear …

[HTML][HTML] Role of immunohistochemistry in the diagnosis of solitary fibrous tumor, a review

B Geramizadeh, M Marzban, A Churg - Iranian journal of pathology, 2016 - ncbi.nlm.nih.gov
Background: Solitary fibrous tumor (SFT) is a mesenchymal tumor which is most commonly
seen in the pleura; however it can be seen in other organs such as the meninge …

Clinicopathologic diversity of undifferentiated sarcoma with BCOR-CCNB3 fusion: analysis of 11 cases with a reappraisal of the utility of immunohistochemistry for …

A Matsuyama, E Shiba, Y Umekita… - The American journal …, 2017 - journals.lww.com
Undifferentiated sarcoma harboring the BCOR-CCNB3 fusion is characterized by its
predilection to affect skeletons of adolescent males, cellular small round/spindle cell …