Glucose metabolism after bariatric surgery: implications for T2DM remission and hypoglycaemia

DA Sandoval, ME Patti - Nature Reviews Endocrinology, 2023 - nature.com
Although promising therapeutics are in the pipeline, bariatric surgery (also known as
metabolic surgery) remains our most effective strategy for the treatment of obesity and type 2 …

MicroRNAs in obesity-associated disorders

EJ Abente, M Subramanian, V Ramachandran… - Archives of biochemistry …, 2016 - Elsevier
The emergence of a worldwide obesity epidemic has dramatically increased the prevalence
of insulin resistance and metabolic syndrome, predisposing individuals to a greater risk for …

Mediterranean diet enriched in extra-virgin olive oil or nuts modulates circulating exosomal non-coding RNAs

DC Mantilla-Escalante, MC Lopez De las Hazas… - European Journal of …, 2021 - Springer
Purpose Exosomes are extracellular vesicles secreted by cells, which can transport different
molecules, including nucleic acids. Dietary habits may induce gene regulation through the …

Green tea prevents NAFLD by modulation of miR‐34a and miR‐194 expression in a high‐fat diet mouse model

LF Torres, B Cogliati, R Otton - Oxidative medicine and cellular …, 2019 - Wiley Online Library
Background/Aims. Nonalcoholic fatty liver disease (NAFLD) is considered the hepatic
manifestation of metabolic syndrome. It is currently the most common chronic liver disease …

Structural characterization and hypolipidemic effect of Cyclocarya paliurus polysaccharide in rat

ZW Yang, KH Ouyang, J Zhao, H Chen, L Xiong… - International Journal of …, 2016 - Elsevier
Polysaccharide is one of the important active ingredients of Cyclocarya paliurus (Batal.)
Iljinskaja leaves. The aims of this work were to analyze the structure of the polysaccharide of …

miR‐212 downregulation contributes to the protective effect of exercise against non‐alcoholic fatty liver via targeting FGF‐21

J Xiao, Y Bei, J Liu… - Journal of cellular …, 2016 - Wiley Online Library
Non‐alcoholic fatty liver disease (NAFLD) is associated with obesity and lifestyle, while
exercise is beneficial for NAFLD. Dysregulated micro RNA s (miRs) control the pathogenesis …

Depleted tumor suppressor miR-107 in plasma relates to tumor progression and is a novel therapeutic target in pancreatic cancer

T Imamura, S Komatsu, D Ichikawa, M Miyamae… - Scientific reports, 2017 - nature.com
This study explored decreased tumor suppressor microRNA (miRNA) plasma levels in
pancreatic cancer (PCa) patients to clarify their potential as novel biomarkers and …

Pathophysiological understanding of HFpEF: microRNAs as part of the puzzle

M Rech, A Barandiarán Aizpurua… - Cardiovascular …, 2018 - academic.oup.com
Half of all heart failure patients have preserved ejection fraction (HFpEF). Comorbidities
associated with and contributing to HFpEF include obesity, diabetes and hypertension. Still …

miR-122 promotes hepatic antioxidant defense of genetically improved farmed tilapia (GIFT, Oreochromis niloticus) exposed to cadmium by directly targeting a …

J Qiang, YF Tao, J He, P Xu, JW Bao, YL Sun - Aquatic Toxicology, 2017 - Elsevier
MicroRNAs (miRNAs) are small, non-coding RNAs that regulate target gene expression by
binding to the 3′ untranslated region (3′ UTR) of the target mRNA. MiRNAs regulate a …

T2DiACoD: a gene atlas of type 2 diabetes mellitus associated complex disorders

J Rani, I Mittal, A Pramanik, N Singh, N Dube… - Scientific reports, 2017 - nature.com
We performed integrative analysis of genes associated with type 2 Diabetes Mellitus (T2DM)
associated complications by automated text mining with manual curation and also gene …