Staphylococcal biofilm development: structure, regulation, and treatment strategies

K Schilcher, AR Horswill - Microbiology and Molecular Biology …, 2020 - Am Soc Microbiol
In many natural and clinical settings, bacteria are associated with some type of biotic or
abiotic surface that enables them to form biofilms, a multicellular lifestyle with bacteria …

Bacterial quorum sensing: its role in virulence and possibilities for its control

ST Rutherford, BL Bassler - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
Quorum sensing is a process of cell–cell communication that allows bacteria to share
information about cell density and adjust gene expression accordingly. This process …

Staphylococcus aureus pathogenesis in diverse host environments

D Balasubramanian, L Harper, B Shopsin… - Pathogens and …, 2017 - academic.oup.com
Staphylococcus aureus is an eminent human pathogen that can colonize the human host
and cause severe life-threatening illnesses. This bacterium can reside in and infect a wide …

Inside job: Staphylococcus aureus host-pathogen interactions

J Horn, K Stelzner, T Rudel, M Fraunholz - International Journal of Medical …, 2018 - Elsevier
Staphylococcus aureus is a notorious opportunistic pathogen causing a plethora of
diseases. Recent research established that once phagocytosed by neutrophils and …

Peptide signaling in the staphylococci

M Thoendel, JS Kavanaugh, CE Flack… - Chemical …, 2011 - ACS Publications
Gram-negative and Gram-positive bacteria have evolved elaborate machinery to
biosynthesize and respond to diverse small-molecule signals. As bacteria grow, these …

[HTML][HTML] (p) ppGpp: magic modulators of bacterial physiology and metabolism

W Steinchen, V Zegarra, G Bange - Frontiers in Microbiology, 2020 - frontiersin.org
When bacteria experience growth-limiting environmental conditions, the synthesis of the
hyperphosphorylated guanosine derivatives (p) ppGpp is induced by enzymes of the …

Capsules of Streptococcus pneumoniae and Other Bacteria: Paradigms for Polysaccharide Biosynthesis and Regulation

J Yother - Annual review of microbiology, 2011 - annualreviews.org
Capsular polysaccharides and exopolysaccharides play critical roles in bacterial survival
strategies, and they can have important medical and industrial applications. An immense …

The Stringent Response of Staphylococcus aureus and Its Impact on Survival after Phagocytosis through the Induction of Intracellular PSMs Expression

T Geiger, P Francois, M Liebeke, M Fraunholz… - PLoS …, 2012 - journals.plos.org
The stringent response is initiated by rapid (p) ppGpp synthesis, which leads to a profound
reprogramming of gene expression in most bacteria. The stringent phenotype seems to be …

Bacterial adaptation during chronic respiratory infections

L Cullen, S McClean - Pathogens, 2015 - mdpi.com
Chronic lung infections are associated with increased morbidity and mortality for individuals
with underlying respiratory conditions such as cystic fibrosis (CF) and chronic obstructive …

Nutrient Limitation Governs Staphylococcus aureus Metabolism and Niche Adaptation in the Human Nose

B Krismer, M Liebeke, D Janek, M Nega… - PLoS …, 2014 - journals.plos.org
Colonization of the human nose by Staphylococcus aureus in one-third of the population
represents a major risk factor for invasive infections. The basis for adaptation of S. aureus to …