The progression of cancer is associated with alterations in the tumor microenvironment,
including changes in extracellular matrix (ECM) composition, matrix rigidity …

The tumor microenvironment is fundamental to cancer progression, and the influence of its
mechanical properties is increasingly being appreciated. Tamoxifen has been used for …

Tamoxifen has been used for many years to target estrogen receptor signalling in breast
cancer cells. Tamoxifen is also an agonist of the G protein-coupled estrogen receptor …

Physical forces and other mechanical stimuli are fundamental regulators of cell behavior
and function. Cells are also biomechanically competent: they generate forces to migrate …

The role of hepatic stellate cells (HSCs) in the development of fibrosis, cirrhosis, and
hepatocellular carcinoma (HCC) has long been the focus of considerable research interest …

Cancer is a disease of dysregulated mechanics which alters cell behaviour, compromises
tissue structure, and promotes tumour growth and metastasis. In the context of tumour …

The mechanical properties of cancer cells differ from that of healthy cells, and include
changes in viscoelasticity, force generation, and mechanosensing, which are associated …

INTRODUÇÃO: Apesar da existência de uma vacina profilática, o vírus de Hepatite B (HBV)
é um importante problema de saúde mundial, sendo responsável por cerca de 257 milhões …