Pulpitis is known as a typical inflammation of dental pulp tissue, and microorganisms of the
oral microbiome are involved in this opportunistic infection. Studies indicated that several …

Aim To investigate the effects of systemically administered melatonin on inflammation and
alveolar bone resorption in rats with experimentally induced periapical lesions. Methodology …

Introduction We have previously shown that intracanal metformin ameliorates apical
periodontitis, partially by modulation of osteoblast apoptosis. The action of metformin on …

Nitric oxide (NO), which is synthesized by the enzyme NO synthase (NOS), is a versatile
endogenous molecule with multiple biological effects on many tissues and organs. In dental …

The purpose of the current study was to compare salivary Nitric oxide and epidermal growth
factor level in diabetic patients and healthy individuals. In this paired-control study 20 …

The blocking of advanced glycation end-products (AGE) has been shown to reduce diabetic
complications and control periodontitis. This study investigated the pattern of palatal wound …

Acute lung injury remains a challenging clinical condition, necessitating the development of
novel, safe and efficient treatments. The prevention of macrophage M1-polarization is a …

We tested the hypothesis that aquaporin-4 (AQP4) knockout (KO) mice might exhibit
abnormal Ca2+ modulating proteins resulting from the exacerbation of pro-inflammatory …

Diabetes is one of the major risk factors for Alzheimer's disease (AD) development. The role
of elevated levels of glucose, methylglyoxal (MGO), and advanced glycation end products …

Naringenin is a flavonoid with several biological activities already reported but with few
biological applications in the pharmaceutical field. In this work, a new flavanone, called …