Chagas disease is one of the most important tropical infections in the world and mainly
affects poor people. The causative agent is the hemoflagellate protozoan Trypanosoma …

The zebrafish has become a widely accepted model host for studies of infectious disease,
including fungal infections. The species is genetically tractable, and the larvae are …

Introduction American trypanosomiasis, better known as Chagas disease, is a global public
health issue. Current treatments targeting the causative parasite, Trypanosoma cruzi, are …

Emerging bio-contaminants such as viruses have affected health and environment settings
of every country. Viruses are the minuscule entities resulting in severe contagious diseases …

Chagas disease (ChD), a complex and persistent parasitosis caused by Trypanosoma cruzi,
represents a natural model of chronic infection, in which some people exhibit cardiac or …

The CD4+ and CD8+ T cell immune response against T. cruzi, the parasite causing Chagas
disease, are relevant for both parasite control and disease pathogenesis. Several studies …

Ambystoma mexicanum is a urodele amphibian endemic to Xochimilco Lake in Mexico, it
belongs to the salamander family Ambystomatidae. This species has frequently been used …

Experimental animals have contributed to basic and translational research on Chagas
disease. Although many species and models have been used depending on the main …

Chagas disease is also a neglected disease, prevalent and endemic in Latin America, but
present in Europe and North America. The main treatment used is benznidazole, but its …

Trypanosoma cruzi, the etiological agent of Chagas disease, is a parasite with variable
tissue tropism according to its genotypic variants. During chronic human infection, cardiac …