Proper functioning of the neural retina relies on the unique retinal environment regulated by
the blood–retinal barrier (BRB), which restricts the passage of solutes, fluids, and toxic …

Background The genetic background of trait variability has captured the interest of ecologists
and animal breeders because the genes that control it could be involved in buffering various …

The diversity and near universal expression of G protein-coupled receptors (GPCR) reflects
their involvement in most physiological processes. The GPCR superfamily is the largest in …

Transcriptional mechanisms that drive angiogenesis and organotypic vascular endothelial
cell specialization are poorly understood. Here, we show that retinal endothelial …

Purpose: To analyze the retino-choroidal vascular characteristics of patients affected by
pigmented paravenous chorio-retinal atrophy by means of optical coherence tomography …

Coronary microvascular disease (CMD) and its progression towards major adverse coronary
events pose a significant health challenge. Accurate in vitro investigation of CMD requires a …

Background Acetaminophen (APAP) overdose is a significant contributor to drug-induced
liver injury worldwide. G-protein–coupled receptor 116 (GPR116) is an important …

Background NK cell is one of innate immune cells and can protect the body from cancer-
initiating cells. It has been reported that GPR116 receptor is involved in inflammation and …

Background In mice, a tri‐layered (superficial, intermediate, and deep) vascular structure is
formed in the retina during the third postnatal week. Short‐term treatment of newborn mice …

Applications This product has been reported to work in the following applications. This
information is derived from testing within our laboratories, peer-reviewed publications or …