Bacterial toxins belong to one of four categories:(i) The classical exo-toxins that are
synthesized by the micro-organisms causing diphtheria, tetanus, and botulism. These were …

At least three different forms of staphylococcal α-toxin have been shown to exist: soluble
active α-toxin (α 3S), soluble inactive α-toxin (α12s), and insoluble inactive aggregate …

Formation of a bacterial brain abscess entails loss of brain cells and formation of pus. The
mechanisms behind the cell loss are not fully understood. Staphylococcus aureus, a …

Stenotrophomonas maltophilia is an important evolving pathogen, especially in patients with
cystic fibrosis (CF), but its mechanism of pathogenesis is poorly understood. The purpose of …

SUMMARY A large batch of enterotoxin A from Staphylococcus aureus strain 196‐E was
prepared in easamino acid medium and concentrated 13.5 times by dialysis under …

Crude hemolysins prepared from various strains of Vibrio parahaemolyticus, which give
positive Kanagawa phenomenon, were partly inactivated by heating at 60 C, but not …

Crude and purified staphylococcal α-toxin were used to demonstrate that the platelet-
damaging effect of crude α-toxin represents a fifth activity of the α-toxin molecule. The …

The purification of staphylococcal β-hemolysin was accomplished by the successive use of
three protein fractionation methods. The first method employed was a double precipitation …

The adenosine diphosphate ribosyl transferase activity of Pseudomonas aeruginosa
exotoxin A (PA toxin) was found to be rapidly destroyed by heating at 45 to 60C but not by …

A factor was found in Vibrio parahaemolyticus which inactivated the hemolytic activity of a
purified, thermostable direct hemolysin. The inactivating factor was associated with the …