Glucose and related sugars repress the transcription of genes encoding enzymes required
for the utilization of alternative carbon sources; some of these genes are also repressed by …

Describes DNA-binding domains which reveal a variety of different designs for recognizing a
specific site on DNA. Presents a brief illustrated taxonomy of those DNA-binding domains for …

The nuclear form of the NF‐kappa B transcription factor binds to DNA as a heterodimer of a
50 kDa (p50) and 65 kDa (p65) polypeptide. The two polypeptides are encoded by different …

A convenient, Agrobacterium‐mediated transient expression assay has been evaluated for
rapid analysis of plant promoters and transcription factors in vivo. By simple infiltration of …

A specific DNA complex of the 65-residue, N-terminal fragment of the yeast transcriptional
activator, GAL4, has been analysed at 2.7 Å resolution by X-ray crystallography. The protein …

The syndecans are transmembrane proteoglycans that place structurally heterogeneous
heparan sulfate chains at the cell surface and a highly conserved polypeptide in the …

The ability of estrogens to stimulate the transcriptional activity of the estrogen receptor can
be inhibited by a diverse range of estrogen antagonists. Here we show that the antiestrogen …

The coevolution of DNA binding proteins and their cognate binding sites is essential for the
maintenance of function. As a result, comparison of DNA binding proteins of unknown …

Foxp3 has been shown to be both necessary and sufficient for the development and function
of naturally arising CD4+ CD25+ regulatory T cells in mice. Mutation of Foxp3 in Scurfy mice …

Activator-dependent transcription in mammalian cells requires upstream stimulatory activity
(USA)-derived cofactors in addition to those present in TFIID. A novel positive cofactor (PC4) …