Heat stress increases human morbidity and mortality compared to normothermic conditions.
Many occupations, disease states, as well as stages of life are especially vulnerable to the …

Cardiovascular diseases (CVD) are the leading cause of death worldwide, and novel
therapies are drastically needed to prevent or delay the onset of CVD to reduce the societal …

Heat and cold stresses have direct impacts on many of the fundamental control mechanisms
of stroke volume, such as preload, afterload, diastolic function or compliance, and systolic …

The earth's climate is changing and increasing ambient heat levels are emerging in large
areas of the world. An important cause of this change is the anthropogenic emission of …

Climate change is a worsening global crisis that will continue negatively impacting
population health and well-being unless adaptation and mitigation interventions are rapidly …

Heat exhaustion is part of a spectrum of heat-related illnesses that can affect all individuals,
although children, older adults, and those with chronic disease are particularly vulnerable …

Non‐technical summary Heat stress reduces brain blood flow and impairs orthostatic
tolerance. Brain blood flow is largely controlled by the partial pressure of arterial. Indeed …

The portion of society aged≥ 60 years is the fastest growing population in the Western
hemisphere. Aging is associated with numerous changes to systemic physiology that affect …

Hyperthermia is an internal body temperature increase above 40.5° C; normally internal
body temperature is kept constant through natural homeostatic mechanisms. Heat-related …

Heat stress profoundly and unanimously reduces orthostatic tolerance. This review aims to
provide an overview of the numerous and multifactorial mechanisms by which this occurs in …