Solid lipid nanoparticles and nanostructured lipid carriers: A review of the methods of manufacture and routes of administration

J Akbari, M Saeedi, F Ahmadi… - Pharmaceutical …, 2022 - Taylor & Francis
The bioavailability of drugs is dependent on several factors such as solubility and the
administration route. A drug with poor aqueous solubility, therefore, poses challenges with …

Nanoparticle-based drug delivery system: the magic bullet for the treatment of chronic pulmonary diseases

S Pramanik, S Mohanto, R Manne… - Molecular …, 2021 - ACS Publications
Chronic pulmonary diseases encompass different persistent and lethal diseases, including
chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), cystic …

Chondroitin/Lactoferrin-dual functionalized pterostilbene-solid lipid nanoparticles as targeted breast cancer therapy

S Aly, AH El-Kamel, E Sheta, SE El-Habashy - International Journal of …, 2023 - Elsevier
Breast cancer remains the leading cause of cancer-associated mortality in women.
Research investigating novel therapeutic approaches is thus crucial, including …

Development and characterization of calcium-alginate beads of apigenin: In vitro antitumor, antibacterial, and antioxidant activities

MF Aldawsari, MM Ahmed, F Fatima, MK Anwer… - Marine Drugs, 2021 - mdpi.com
The objective of this work was to develop sustained-release Ca-alginate beads of apigenin
using sodium alginate, a natural polysaccharide. Six batches were prepared by applying the …

Design and evaluation of solid lipid nanoparticles loaded topical gels: repurpose of fluoxetine in diabetic wound healing

F Fatima, M Aleemuddin, MM Ahmed, MK Anwer… - Gels, 2022 - mdpi.com
The current study aimed to prepare a topical gel containing solid lipid nanoparticles (SLNs)
encapsulating fluoxetine for diabetic wound healing effects. Fluoxetine (FX) was loaded into …

Green synthesized silver nanoparticles using tridax procumbens for topical application: Excision wound model and histopathological studies

F Fatima, MF Aldawsari, MM Ahmed, MK Anwer, M Naz… - Pharmaceutics, 2021 - mdpi.com
The objective of this study was to synthesize silver nanoparticles from the leaves of Tridax
procumbens and develop its topical gels using chitosan to investigate the wound healing …

Ribociclib-loaded ethylcellulose-based nanosponges: Formulation, physicochemical characterization, and cytotoxic potential against breast cancer

MM Ahmed, F Fatima, A Alali… - Adsorption Science …, 2022 - journals.sagepub.com
In the present study, ribociclib-loaded nanosponges (RCNs) composed of ethylcellulose and
polyvinyl alcohol were developed using an emulsion-solvent evaporation method …

[HTML][HTML] Solid lipid nanoparticles for efficient oral delivery of tyrosine kinase inhibitors: a nano targeted cancer drug delivery

S Satapathy, CS Patro - Advanced Pharmaceutical Bulletin, 2022 - ncbi.nlm.nih.gov
Tyrosine kinase inhibitors (TKIs) are used as targeted therapy for cancer by inhibiting the
signaling pathway and tumor growth. Many TKIs got approved by FDA in recent times for the …

Mechanisms of solid lipid nanoparticles-triggered signaling pathways in eukaryotic cells

T Moraes-Lacerda, MB de Jesus - Colloids and Surfaces B: Biointerfaces, 2022 - Elsevier
Solid lipid nanoparticles (SLN) are used in various fields such as pharmaceutical, cosmetic,
and biomedical research and show promising results in delivering biomolecules. SLN …

Formulation of chitosan-coated brigatinib nanospanlastics: optimization, characterization, stability assessment and in-vitro cytotoxicity activity against H-1975 cell lines

RM Zaki, MM Alfadhel, SM Alshahrani, A Alsaqr… - Pharmaceuticals, 2022 - mdpi.com
The purpose of the current study was to develop Brigatinib (BGT)-loaded nanospanlastics
(BGT-loaded NSPs)(S1-S13) containing Span 60 with different edge activators (Tween 80 …