Development of computational small animal models and their applications in preclinical imaging and therapy research

T Xie, H Zaidi - Medical physics, 2016 - Wiley Online Library
The development of multimodality preclinical imaging techniques and the rapid growth of
realistic computer simulation tools have promoted the construction and application of …

Single-cell tracking with PET using a novel trajectory reconstruction algorithm

KS Lee, TJ Kim, G Pratx - IEEE transactions on medical …, 2014 - ieeexplore.ieee.org
Virtually all biomedical applications of positron emission tomography (PET) use images to
represent the distribution of a radiotracer. However, PET is increasingly used in cell tracking …

Cold wall effect eliminating method to determine the contrast recovery coefficient for small animal PET scanners using the NEMA NU-4 image quality phantom

I Lajtos, J Czernin, M Dahlbom, F Daver… - Physics in Medicine …, 2014 - iopscience.iop.org
The contrast recovery coefficients (CRC) were evaluated for five different small animal PET
scanners: GE Explore Vista, Genisys4, MiniPET-2, nanoScan PC and Siemens Inveon. The …

Numerical algorithms for scatter-to-attenuation reconstruction in PET: empirical comparison of convergence, acceleration, and the effect of subsets

Y Berker, JS Karp, V Schulz - IEEE transactions on radiation …, 2017 - ieeexplore.ieee.org
The use of scattered coincidences for the attenuation correction of positron emission
tomography data has recently been proposed. For practical applications, convergence …

Evaluation of attenuation and scatter correction requirements as a function of object size in small animal PET imaging

A Konik, T Koesters, MT Madsen… - IEEE Transactions on …, 2011 - ieeexplore.ieee.org
In human emission tomography, an additional transmission scan (x-ray CT or external
gamma-source) is often required to obtain accurate attenuation maps for attenuation …

Oxygen-15 labeled CO2, O2, and CO PET in small animals: evaluation using a 3D-mode microPET scanner and impact of reconstruction algorithms

G Horitsugi, T Watabe, Y Kanai, H Ikeda, H Kato… - Ejnmmi Research, 2017 - Springer
Background Positron emission tomography (PET) studies using 15 O-labeled CO 2, O 2, and
CO have been used in humans to evaluate cerebral blood flow (CBF), the cerebral oxygen …

Evaluation of the feasibility and quantitative accuracy of a generalized scatter 2D PET reconstruction method

H Sun, S Pistorius - International Scholarly Research Notices, 2013 - Wiley Online Library
Scatter degrades the contrast and quantitative accuracy of positron emission tomography
(PET) images, and most methods for estimating and correcting scattered coincidences in …

NEMA NU 4-2008 validation and applications of the PET-SORTEO Monte Carlo simulations platform for the geometry of the Inveon PET preclinical scanner

F Boisson, CJ Wimberley, W Lehnert… - Physics in Medicine …, 2013 - iopscience.iop.org
Monte Carlo-based simulation of positron emission tomography (PET) data plays a key role
in the design and optimization of data correction and processing methods. Our first aim was …

GATE simulations of small animal SPECT for determination of scatter fraction as a function of object size

A Konik, MT Madsen… - IEEE Transactions on …, 2012 - ieeexplore.ieee.org
In human emission tomography, combined PET/CT and SPECT/CT cameras provide
accurate attenuation maps for sophisticated scatter and attenuation corrections. Having …

A simulation study for estimating scatter fraction in whole-body 18F-FDG PET/CT

S Hosokawa, K Inoue, D Kano, F Shimizu… - … Physics and Technology, 2017 - Springer
Abstract Whereas Monte Carlo (MC) simulation is widely utilized in estimation of the scatter
component, a simulation model which can calculate the scatter fraction (SF) of each patient …