Understanding environmental contributions to autism: Causal concepts and the state of science

I Hertz‐Picciotto, RJ Schmidt, P Krakowiak - Autism Research, 2018 - Wiley Online Library
The complexity of neurodevelopment, the rapidity of early neurogenesis, and over 100 years
of research identifying environmental influences on neurodevelopment serve as backdrop to …

Preconception and prenatal nutrition and neurodevelopmental disorders: a systematic review and meta-analysis

M Li, E Francis, SN Hinkle, AS Ajjarapu, C Zhang - Nutrients, 2019 - mdpi.com
Preconception and prenatal nutrition is critical for fetal brain development. However, its
associations with offspring neurodevelopmental disorders are not well understood. This …

Maternal Multivitamin Intake, Plasma Folate and Vitamin B12 Levels and Autism Spectrum Disorder Risk in Offspring

R Raghavan, AW Riley, H Volk… - Paediatric and …, 2018 - Wiley Online Library
Background To examine the prospective association between multivitamin supplementation
during pregnancy and biomarker measures of maternal plasma folate and vitamin B12 …

Association of maternal use of folic acid and multivitamin supplements in the periods before and during pregnancy with the risk of autism spectrum disorder in offspring

SZ Levine, A Kodesh, A Viktorin, L Smith… - JAMA …, 2018 - jamanetwork.com
Importance The association of maternal use of folic acid and multivitamin supplements
before and during pregnancy with the risk of autism spectrum disorder (ASD) in offspring is …

Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial

RE Frye, J Slattery, L Delhey, B Furgerson… - Molecular …, 2018 - nature.com
We sought to determine whether high-dose folinic acid improves verbal communication in
children with non-syndromic autism spectrum disorder (ASD) and language impairment in a …

The generation R study: biobank update 2015

CJ Kruithof, MN Kooijman, CM van Duijn… - European journal of …, 2014 - Springer
Abstract The Generation R Study is a population-based prospective cohort study from fetal
life until adulthood. The study is designed to identify early environmental and genetic causes …

New perspective on impact of folic acid supplementation during pregnancy on neurodevelopment/autism in the offspring children–a systematic review

Y Gao, C Sheng, R Xie, W Sun, E Asztalos… - PloS one, 2016 - journals.plos.org
It has been conclusively established that folic acid supplementation prior to and during early
pregnancy (up to 12 weeks of gestation) can prevent neural tube defects (NTDs). We …

Folic acid and autism: a systematic review of the current state of knowledge

B Hoxha, M Hoxha, E Domi, J Gervasoni, S Persichilli… - Cells, 2021 - mdpi.com
Folic acid has been identified to be integral in rapid tissue growth and cell division during
fetal development. Different studies indicate folic acid's importance in improving childhood …

Combined prenatal pesticide exposure and folic acid intake in relation to autism spectrum disorder

RJ Schmidt, V Kogan, JF Shelton… - Environmental …, 2017 - ehp.niehs.nih.gov
Background: Maternal folic acid (FA) protects against developmental toxicity from certain
environmental chemicals. Objective: We examined combined exposures to maternal FA and …

Neurodevelopmental effects of maternal folic acid supplementation: A systematic review and meta-analysis

H Chen, L Qin, R Gao, X Jin, K Cheng… - Critical Reviews in …, 2023 - Taylor & Francis
Folic acid, a water-soluble vitamin B nutrient, plays an important role not only in maintaining
a healthy pregnancy but also in offspring brain development and function, however, it …