Oral squamous cell carcinoma (OSCC) is the most prevalent oral malignant tumor
worldwide. An early diagnosis can have a major positive impact on its prognosis. Human …

Saliva testing is a vital method for clinical applications, for its noninvasive features, richness
in substances, and the huge amount. Due to its direct anatomical connection with oral …

Background and Objectives: The research aimed at evaluating the capacity of salivary
exosomal miR-10b-5p and miR-486-5p for oral and oropharyngeal cancer detection …

Simple Summary Head and neck cancer remains a challenging and deadly disease as it is
often identified in more advanced stages due to limitations in screening and surveillance …

Cancer is the most challenging health complication worldwide. Scientific society has tried to
decode its complications and is developing a smart solution for mankind. Extracellular …

Raman spectroscopy recently proved a tremendous capacity to identify disease-specific
markers in various (bio) samples being a non-invasive, rapid, and reliable method for cancer …

Oral lichen planus (OLP) is a premalignant disease with unknown etiology. It has been
demonstrated that inflammation and immune activation play a central role in the …

Head and neck cancers (HNCs) comprise a heterogeneous group of tumors that extend from
the oral cavity to the upper gastrointestinal tract. The principal etiologic factors for oral …

Extracellular vesicles, as bioactive molecules, have been extensively studied. There are
abundant studies in the literature on their biogenesis, secretion, structure, and content, and …

Small extracellular vesicles (sEV) are a class of extracellular vesicles (30–150 nm),
delivering molecules including proteins, metabolites, and microRNAs (miRNAs), involved in …