Sulfur (S VI) based moieties, especially, the sulfonyl or sulfonamide based analogues have
showed a variety of pharmacological properties, and its derivatives propose a high degree …

Piperazine is one of the most sought heterocyclics for the development of new drug
candidates. This ring can be traced in a number of well established, commercially available …

Nitrogen sulphur containing heterocycles have specific properties due to which they can be
used as a potential material in a different type of industries such as medicinal …

To improve the teaching-learning process in the Medicinal Chemistry course, new strategies
have been incorporated into practical classes of this fundamental discipline of the …

Phthalimides functionalized with cyclic amines were synthesized, characterized and
screened for their in vitro antimalarial efficacy against Plasmodium falciparum (Pf3D7). Of all …

Pyrazole and propenone quinoxaline derivatives were tested against intracellular forms of
Leishmania peruviana and Trypanosoma cruzi. Both series were tested for toxicity against …

Piperazine and pyrrolidine derivatives were synthesised and evaluated for their capacity to
inhibit the growth of Plasmodium falciparum chloroquine-resistant (FCR-3) strain in culture …

A novel class of phthalimides functionalized with privileged scaffolds was designed,
synthesized and evaluated as potential inhibitors of plasmepsin 2 (Ki: 0.99±0.1 μM for 6u) …

Malaria and leishmaniasis are two of the World's most important tropical parasitic diseases.
Thirteen new 2-cyano-3-(4-phenylpiperazine-1-carboxamido) quinoxaline 1, 4-dioxide …

The challenge of controlling and eventually eradicating malaria means that new tools are
urgently needed. South America's role in this fight spans both ends of the research and …