Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …

Invasive fungal infections in humans are generally associated with high mortality, making
the choice of antifungal drug crucial for the outcome of the patient. The limited spectrum of …

Plant antimicrobial peptides (AMPs) have evolved differently from AMPs from other life
forms. They are generally rich in cysteine residues which form multiple disulfides. In turn, the …

Despite the great strides in healthcare during the last century, some challenges still
remained unanswered. The development of multi-drug resistant bacteria, the alarming …

Plant defensins are an extensive family of small cysteine rich proteins characterised by a
conserved cysteine stabilised alpha beta protein fold which resembles the structure of insect …

Extracellular vesicles (EVs) are membranous vesicles that are released by cells. In this
study, the role of the Endosomal Sorting Complex Required for Transport (ESCRT) …

Plant defensins are small, cysteine-rich peptides that possess biological activity towards a
broad range of organisms. Their activity is primarily directed against fungi, but bactericidal …

Defensins are a well-characterised group of small, disulphide-rich, cationic peptides that are
produced by essentially all eukaryotes and are highly diverse in their sequences and …

Introduction Candida albicans is the most prevalent fungal pathogen in humans. Due to the
development of drug resistance, there is today a need for new antifungal agents for the …

The incidence of invasive fungal infections is increasing worldwide, resulting in more than
1.6 million deaths every year. Due to growing antifungal drug resistance and the limited …