Early diagnostics and early intervention in neurodevelopmental disorders—age-dependent challenges and opportunities

M Hadders-Algra - Journal of clinical medicine, 2021 - mdpi.com
This review discusses early diagnostics and early intervention in developmental disorders in
the light of brain development. The best instruments for early detection of cerebral palsy …

Preterm brain injury, antenatal triggers, and therapeutics: timing is key

DRMG Ophelders, R Gussenhoven, L Klein… - Cells, 2020 - mdpi.com
With a worldwide incidence of 15 million cases, preterm birth is a major contributor to
neonatal mortality and morbidity, and concomitant social and economic burden Preterm …

Neuroimaging in the term newborn with neonatal encephalopathy

JL Wisnowski, P Wintermark, SL Bonifacio… - Seminars in Fetal and …, 2021 - Elsevier
Neuroimaging is widely used to aid in the diagnosis and clinical management of neonates
with neonatal encephalopathy (NE). Yet, despite widespread use clinically, there are few …

Magnetic resonance imaging in (Near-) Term infants with hypoxic-ischemic encephalopathy

CEJ Parmentier, LS de Vries, F Groenendaal - Diagnostics, 2022 - mdpi.com
Hypoxic-ischemic encephalopathy (HIE) is a major cause of neurological sequelae in (near-
) term newborns. Despite the use of therapeutic hypothermia, a significant number of …

Methods for assessing the severity of perinatal asphyxia and early prognostic tools in neonates with hypoxic-ischemic encephalopathy treated with therapeutic …

W Walas, M Wilińska… - Advances in Clinical …, 2020 - repo.uni.opole.pl
Despite theprogress inperinatal care, perinatal asphyxia (PA) remains asignificant problem
inneonatology. Thedevelopment of therapeutic hypothermia (TH) has improved …

Neonatal hypoxic-ischemic encephalopathy spectrum: severity-stratified analysis of neuroimaging modalities and association with neurodevelopmental outcomes

MN Cizmeci, D Wilson, M Singhal, A El Shahed… - The Journal of …, 2024 - Elsevier
Objective To compare hypoxic-ischemic injury on early cranial ultrasonography (cUS) and
post-rewarming brain magnetic resonance imaging (MRI) in newborn infants with hypoxic …

[HTML][HTML] LXA4 protects against hypoxic-ischemic damage in neonatal rats by reducing the inflammatory response via the IκB/NF-κB pathway

J Zhu, B Yu, C Fu, M He, J Zhu, B Chen, Y Zheng… - International …, 2020 - Elsevier
Hypoxia and the resultant decreases in cerebral blood flow in the perinatal period can lead
to neonatal hypoxic-ischemic (HI) brain injury, which can, in turn, cause severe disability or …

[HTML][HTML] Deep medullary vein thrombosis in newborns: a systematic literature review

JN Pin, L Leonardi, M Nosadini, MF Pelizza, L Capato… - Neonatology, 2023 - karger.com
Background: Deep medullary vein (DMV) thrombosis is a rare cause of brain damage in
both preterm and full-term neonates. In this study, we aimed to collect data on clinical and …

[HTML][HTML] Clinical Prediction Models and Predictors for Death or Adverse Neurodevelopmental Outcome in Term Newborns with Hypoxic-Ischemic Encephalopathy: A …

JF Langeslag, K Berendse, JG Daams, W Onland… - Neonatology, 2023 - karger.com
Background: Although many predictive parameters have been studied, an internationally
accepted, validated predictive model to predict the clinical outcome of asphyxiated infants …

Value of cranial ultrasound at initiation of therapeutic hypothermia for neonatal encephalopathy

W Sanislow, E Singh, E Yang, T Inder… - Journal of …, 2022 - nature.com
Objective There is variation in the clinical practice for the use of cranial ultrasound (cUS) at
the time of initiation of therapeutic hypothermia (TH) for neonatal encephalopathy. The role …