Synthetic applications of hydride abstraction reactions by organic oxidants

JL Miller, JMIA Lawrence, FOR Del Rey… - Chemical Society …, 2022 - pubs.rsc.org
Carbon–hydrogen bond functionalizations provide an attractive method for streamlining
organic synthesis, and many strategies have been developed for conducting these …

Strategic Applications of the β‐Silicon Effect

DD Roberts, MG McLaughlin - Advanced Synthesis & Catalysis, 2022 - Wiley Online Library
Organosilicon reagents are highly versatile and privileged scaffolds in modern synthetic
chemistry, largely due to the range of transformations the groups are amenable to. The β …

Predictive model for oxidative C–H bond functionalization reactivity with 2, 3-dichloro-5, 6-dicyano-1, 4-benzoquinone

CA Morales-Rivera, PE Floreancig… - Journal of the American …, 2017 - ACS Publications
2, 3-Dichloro-5, 6-dicyano-1, 4-benzoquinone (DDQ) is a highly effective reagent for
promoting C–H bond functionalization. The oxidative cleavage of benzylic and allylic C–H …

Efficient Indirect Electrochemical Synthesis of 2‐Substituted Benzoxazoles using Sodium Iodide as Mediator

WC Li, CC Zeng, LM Hu, HY Tian… - Advanced Synthesis & …, 2013 - Wiley Online Library
Efficient Indirect Electrochemical Synthesis of 2‐Substituted Benzoxazoles using Sodium Iodide
as Mediator - Li - 2013 - Advanced Synthesis & Catalysis - Wiley Online Library Skip to Article …

Construction of N‐heterocycles through cyclization of tertiary amines

S Liu, Z Zhao, Y Wang - Chemistry–A European Journal, 2019 - Wiley Online Library
N‐Heterocycles have been found in a large number of natural products, drug molecules,
and bioactive compounds, and they thereby play a vital role in diverse research disciplines …

The aza‐Prins reaction in the synthesis of natural products and analogues

BV Subba Reddy, PN Nair, A Antony… - European Journal of …, 2017 - Wiley Online Library
The classical Prins cyclization reaction has been one of the most studied reactions during
the last two decades and it has found many applications in key steps of natural product …

Synthesis of Fluorinated Benzo[a]quinolizidines via Visible Light‐induced Tandem Substitution of Two Fluorine Atoms in a CF3 Group

H Chen, T Xiao, L Li, D Anand, Y He… - Advanced Synthesis & …, 2017 - Wiley Online Library
An efficient method for the construction of fluorinated benzo [a] quinolizidines from α‐
trifluoromethyl alkenes and dihydroisoquinoline acetic acids using visible light …

Synthesis of sulfur-containing heterocycles through oxidative carbon–hydrogen bond functionalization

Y Cui, PE Floreancig - Organic letters, 2012 - ACS Publications
Vinyl sulfides react rapidly and efficiently with 2, 3-dichloro-5, 6-dicyano-1, 4-benzoquinone
(DDQ) to form α, β-unsaturated thiocarbenium ions through oxidative carbon–hydrogen …

Aromatic Cations from Oxidative Carbon–Hydrogen Bond Cleavage in Bimolecular Carbon–Carbon Bond Forming Reactions

DJ Clausen, PE Floreancig - The Journal of organic chemistry, 2012 - ACS Publications
Chromenes and isochromenes react quickly with 2, 3-dichloro-5, 6-dicyano-1, 4-
benzoquinone (DDQ) to form persistent aromatic oxocarbenium ions through oxidative …

Mechanism‐Based Approach to Reagent Selection for Oxidative Carbon− Hydrogen Bond Cleavage Reactions

JL Miller, L Zhou, P Liu… - Chemistry–A European …, 2022 - Wiley Online Library
Numerous hydride‐abstracting agents generate the same cationic intermediate, but
substrate features such as intermediate cation stability, oxidation potential, and steric …