Novel disease-modifying treatments for neuropathic pain are urgently required. The cellular
immune response to nerve injury represents a promising target for therapeutic development …

Non-steroidal anti-inflammatory drugs (NSAIDs) are the most widely used analgesics to treat
inflammatory pain. Despite their efficacy, recent studies show that NSAID use in early acute …

Chronic pain is a common problem, with more than one-fifth of adult Americans reporting
pain daily or on most days. It adversely affects the quality of life and imposes substantial …

Chronic pain is a constantly recurring and persistent illness, presenting a formidable
healthcare challenge for patients and physicians alike. Current first‐line analgesics offer …

STUDY QUESTION What are the similarities and differences in the systemic proteomic
profiles by endometriosis-associated pain subtypes among adolescents and young adults …

Despite the worldwide prevalence and huge burden of pain, pain is an undertreated
phenomenon. Currently used analgesics have several limitations regarding their efficacy …

Background Chronic pain is a common, poorly understood condition. Genetic studies
including genome-wide association studies have identified many relevant variants, which …

Chronic stress and chronic pain share neuro-anatomical, endocrinological, and biological
features. However, stress prepares the body for challenging situations or mitigates tissue …

Chronic pain is a common problem, with more than one-fifth of adult Americans reporting
pain daily or on most days. It adversely affects quality of life and imposes substantial …

In the last few years there has been an increased appreciation that pain perception in
rheumatic and musculoskeletal diseases (RMDs) has several mechanisms which include …