Covering: 2010 to 2022 Heterologous expression of natural product biosynthetic gene
clusters (BGCs) has become a widely used tool for genome mining of cryptic pathways …

Filamentous fungi produce a vast number of bioactive secondary metabolites (SMs), some of
which have found applications in the pharmaceutical industry including as antibiotics and …

Genome mining is a promising method to discover novel secondary metabolites in the
postgenomic era. We applied the Aspergillus oryzae heterologous expression system to …

Covering: 2014 up to the third quarter of 2019 Entomopathogens constitute a unique,
specialized trophic subgroup of fungi, most of whose members belong to the order …

The sorbicillinoids are a class of biologically active and structurally diverse fungal
polyketides arising from sorbicillin. Through co‐expression of sorA, sorB, sorC, and sorD …

To develop the versatile methodology for genome mining of mushroom metabolites, we
examined the production of bioactive diterpenes erinacines using genomic DNA sequences …

Fusaric acid (FA) is a well-known mycotoxin that plays an important role in plant pathology.
The biosynthetic gene cluster for FA has been identified, but the biosynthetic pathway …

Fungal natural products comprise a wide range of bioactive compounds including important
drugs and agrochemicals. Intriguingly, bioinformatic analyses of fungal genomes have …

High throughput genome sequencing has revealed a multitude of potential secondary
metabolites biosynthetic pathways that remain cryptic. Pathway reconstruction coupled with …

The biosynthetic machinery of the first fungal ribosomally synthesized and post‐
translationally modified peptide (RiPP) ustiloxin B was elucidated through a series of gene …