Molecular mechanisms underlying the action of carcinogens in gastric cancer with a glimpse into targeted therapy

E Patrad, S Khalighfard, T Amiriani, V Khori… - Cellular Oncology, 2022 - Springer
Background Gastric cancer imposes a substantial global health burden despite its overall
incidence decrease. A broad spectrum of inherited, environmental and infectious factors …

[HTML][HTML] Relevance of miR-223 as potential diagnostic and prognostic markers in cancer

F Aziz, A Chakraborty, I Khan, J Monts - Biology, 2022 - mdpi.com
Simple Summary MicroRNAs (miRNAs) are endogenous small non-coding RNAs that
function in the regulation of gene expression and regulate a wide array of biological …

Use of bidirectional Mendelian randomization to unveil the association of Helicobacter pylori infection and autoimmune thyroid diseases

K Wang, Q Zhang, P Zhang, Q Yang, F Pan, B Zha - Science Advances, 2024 - science.org
Previous observational studies found associations between Helicobacter pylori infection and
autoimmune thyroid diseases (AITDs), but the causal nature of this association is still …

[HTML][HTML] How gut microbiota are shaped by pattern recognition receptors in colitis and colorectal cancer

F Qing, T Xie, L Xie, T Guo, Z Liu - Cancers, 2022 - mdpi.com
Simple Summary The pathogenesis of intestinal inflammatory disorders such as colitis and
colorectal cancer is complicated and dysregulation of gut microbiota is considered an …

[HTML][HTML] α1, 3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation

H Wang, X Cui, L Wang, N Fan, M Yu, H Qin… - Cell Death & …, 2023 - nature.com
Embryo implantation into the uterus is the gateway for successful pregnancy. Proper
migration and invasion of embryonic trophoblast cells are the key for embryo implantation …

MiR-507 inhibits the progression of gastric carcinoma via targeting CBX4-mediated activation of Wnt/β-catenin and HIF-1α pathways

X Fang, A Pan - Clinical and Translational Oncology, 2022 - Springer
Purpose Gastric carcinoma (GC) is a common malignant disease with high morbidity and
mortality. MiR-507 has been confirmed as a tumor inhibitor which can suppress the …

Sialyl Lewis X mediates interleukin-1 beta-induced trophoblast adhesion to endometrial cells during human embryo implantation

Z Ma, M Kessler, A Chelariu-Raicu… - Biology of …, 2023 - academic.oup.com
Cell surface carbohydrate antigens sialyl Lewis X (sLeX) and Lewis Y (LeY) are paramount
glycoconjugates and are abundantly expressed in the receptive endometrium. Furthermore …

[HTML][HTML] Glycan expression profile of signet ring cell gastric cancer cells and potential applicability of rBC2LCN-targeted lectin drug conjugate therapy

Y Yang, Y Akashi, O Shimomura, H Tateno, S Saito… - Gastric Cancer, 2022 - Springer
Background Signet ring cell carcinoma (SRC) is a distinct subtype of gastric cancer (GC);
however, the specific characteristics of cancer cell surface glycans and glycosylation remain …

[HTML][HTML] Sugiol Masters Apoptotic Precision to Halt Gastric Cancer Cell Proliferation

T Bakhsh, SS Abuzahrah, SH Qahl, MA Akela… - Pharmaceuticals, 2023 - mdpi.com
Sugiol, a natural compound with anticancer properties, has shown promise in various
cancer types, but its potential in preventing gastric cancer remains uncertain. In this study …

Quercetin Promotes Apoptosis of Gastric Cancer Cells through the EGFR‐ERK Signaling Pathway

Y Liu, Y Li, Y Jiang, X Zheng, T Wang… - Journal of Food …, 2024 - Wiley Online Library
Previous studies have shown that various active components of licorice have anticancer
effects. However, few studies have investigated the mechanism of action of licorice in gastric …