Regulated cell death mediated by dedicated molecular machines, known as programmed
cell death, plays important roles in health and disease. Apoptosis, necroptosis and …

Objectives and design Chlorogenic acid, which belongs to the polyphenols, is an anti-
oxidant and anti-obesity agent. In this study, we investigated the role of chlorogenic acid in …

Alzheimer's disease (AD) is the most common cause of dementia in older adults.
Neuropathological and imaging studies have demonstrated a progressive and stereotyped …

Lytic cell death culminates in cell swelling and plasma membrane rupture (PMR). The
cellular contents released, including proteins, metabolites, and nucleic acids, can act as …

Abstract Ninjurin1 (Ninj1), an adhesion molecule, regulates macrophage function in hyaloid
regression, multiple sclerosis, and atherosclerosis. However, its biological relevance and …

Triple-negative breast cancer (TNBC) represents a highly aggressive form of breast cancer
with limited treatment options. Proinflammatory cytokines such as TNFα can facilitate tumor …

Objectives and design Arbutin, which is found in the genus Arctostaphylos, is an anti-oxidant
and a depigmenting agent. The present study was designed to validate the anti …

Background & Aims Liver ischemia-reperfusion (IR) injury represents a major risk factor in
both partial hepatectomy and liver transplantation. Nerve injury–induced protein 1 (Ninj1) is …

Background The hypoxia-inducible factor-1 (HIF-1) is known to play an important role in
cellular responses to hypoxia, including the transcriptional activation of a number of genes …

Here we developed a novel green synthesis method for gold nanoparticles (CGA-AuNPs)
using chlorogenic acid (CGA) as reductants without the use of other chemicals and validated …