The coronavirus disease 2019 (COVID-19) pandemic has elicited a swift response by the
scientific community to elucidate the pathogenesis of severe acute respiratory syndrome …

JCI - Differential roles of regulatory T cells in acute respiratory infections Go to JCI Insight About
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Aim and objective Emerging translational evidence suggests that epigenetic alterations
(DNA methylation, miRNA expression, and histone modifications) occur after external stimuli …

BACKGROUND Checkpoint inhibitor pneumonitis (CIP) is a highly morbid complication of
immune checkpoint immunotherapy (ICI), one which precludes the continuation of ICI. Yet …

Acute respiratory distress syndrome (ARDS) is a clinical syndrome associated with
oxygenation failure resulting from a direct pulmonary or indirect systemic insult. It is a …

Acute respiratory distress syndrome/acute lung injury (ALI) was described in 1967. The
uncontrolled inflammation is a central issue of the syndrome. The regulatory T cells (Tregs) …

Background Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are
severe inflammatory lung diseases. Methylprednisolone (MP) is a common drug against …

DNA methylation is a dynamic epigenetic modification with a prominent role in determining
mammalian cell development, lineage identity, and transcriptional regulation. Primarily …

DNA methylation represents a fundamental epigenetic mark that is associated with
transcriptional repression during development, maintenance of homeostasis, and disease …

The acute respiratory distress syndrome (ARDS) is a devastating illness characterized by
severe hypoxemia and diffuse alveolar damage. Direct lung infection is the leading cause of …