Injured peripheral nerves but not central nerves have the capacity to regenerate and
reinnervate their target organs. After the two most severe peripheral nerve injuries of six …

Peripheral nerve injury (PNI), one of the most common concerns following trauma, can result
in a significant loss of sensory or motor function. Restoration of the injured nerves requires a …

Peripheral nerves are particularly vulnerable to injuries and are involved in numerous
pathologies for which specific treatments are lacking. This review summarizes the …

Commercial nerve guidance conduits (NGCs) for repair of peripheral nerve discontinuities
are of little use in gaps larger than 30 mm, and for smaller gaps they often fail to compete …

The extracellular environment of the central nervous system (CNS) becomes highly
structured and organized as the nervous system matures. The extracellular space of the …

Peripheral nerve injury (PNI) is a major clinical problem that may lead to different levels of
sensory and motor dysfunction including paralysis. Due to the high disability rate and …

Local application of exogenous agents with neurotrophic properties enhances the
regenerative capacity of injured neurons, especially following reconstructions of long nerve …

Peripheral nerve damage is a common clinical complication of traumatic injury occurring
after accident, tumorous outgrowth, or surgical side effects. Although the new methods and …

This review identifies some key concepts of muscle regeneration, viewed from perspectives
of classical and modern research. Early insights noted the pattern and sequence of …

Introduction Rat sciatic nerve injury (PNR) is the most utilized model in studies on peripheral
nerve regeneration. However, large animal models are increasingly favored based on the …