Squamous cell carcinoma of the head and neck (SCCHN) is a group of cancers of epithelial
origin that may provide an ideal model for the study of gene-environment interaction …

Carcinogenesis is the result of a series of genetic mutations resulting in unregulated growth
of a clone of cells and the development of malignant lesion that is largely monoclonal …

PURPOSE: To report atypical clinical behavior observed in human papillomavirus (HPV)–
related oropharyngeal carcinoma (OPC) treated with radiotherapy. METHODS AND …

Abstract Objectives/Hypothesis: Clinical and molecular patterns of head and neck squamous
cell carcinoma (HNSCC) in nonsmokers and smokers may be different. Analysis of these …

Background The prolongation of life expectancy results in an increasing number of
malignant neoplasms occurring in the elderly population. For a long time these patients …

Introduction It is the opinion of many surgeons that the biologic potential of cancer that
develops in young people is different compared with older patients. Prior reports on small …

The percentage of elderly people with head and neck cancers (HNC) is rising due to
increasing average lifespan. As with younger patients, elderly patients require a …

Background: An increase in the incidence of oral cancer among patients younger than 40
years has been reported worldwide. It has been suggested that the disease behaves more …

Background Elderly patients over 80 years of age represent a growing population, some of
whom have complex medical problems that are compounded by the presence of upper …

Objective To provide surgeons and clinicians with a critical review of microvascular
reconstructive options and their expected outcomes after head and neck cancer resection in …