Parental History of Memory Impairment and β-Amyloid in Cognitively Unimpaired Older Adults

M Seto, TJ Hohman, EC Mormino, KV Papp… - JAMA …, 2024 - jamanetwork.com
Importance Studies have suggested that maternal history of late-onset Alzheimer disease,
but not paternal, predisposes individuals to higher brain β-amyloid (Aβ) burden, reduced …

β-Amyloid in Cognitively Unimpaired Individuals—Blame Mom?

DB Dubal, HC Elser - JAMA neurology, 2024 - jamanetwork.com
Family history is one of the biggest risk factors—behind advanced age—for developing late-
onset Alzheimer disease (AD). This is especially true if the family history involves a …

X-chromosome-wide association study for Alzheimer's disease

J Le Borgne, L Gomez, S Heikkinen, N Amin, S Ahmad… - medRxiv, 2024 - medrxiv.org
Due to methodological reasons, the X-chromosome has not been featured in the major
genome-wide association studies on Alzheimer's Disease (AD). To finally address this and …

Advancing Genetic Studies in Latin American Populations: Enhancing Imputation and Investigating X Chromosome Associations With Alzheimer's Disease

JN French - 2024 - search.proquest.com
Estimating genetic risk factors of diseases is challenging in diverse populations
underrepresented in genomic studies. Genome-wide association studies (GWAS) are …