Depression is one of the most frequent and burdensome non-motor symptoms in
Parkinson's disease (PD), across all stages. Even when its severity is mild, PD depression …

The etiology of Parkinson's disease (PD) is not well understood but likely to involve both
genetic and environmental factors. Incidence and prevalence estimates vary to a large …

The clinical diagnosis of Parkinson's disease rests on the identification of the characteristics
related to dopamine deficiency that are a consequence of degeneration of the substantia …

It is reasonably well established that prior to the motor phase of classical Parkinson's
disease (PD) there is a prodromal period of several years duration. Once typical motor …

Background We postulated that idiopathic rapid-eye-movement (REM) sleep behaviour
disorder (IRBD) represents the prodromal phase of a Lewy body disorder and that, with …

Non-motor symptoms (NMS) of Parkinson's disease remain the most under-appreciated and
under-researched when taken as a whole. Data is emerging that it is the “totaL” burden of …

Epidemiological research aims to provide information on the development, prevalence and
progression of diseases, and their associated risk factors. Epidemiological research is thus …

Parkinson's disease (PD) is a common neurodegenerative disorder with prominent loss of
nigro‐striatal dopaminergic neurons. The resultant dopamine (DA) deficiency underlies the …

Objective: To investigate the long-term risk of Parkinson disease (PD) after depression and
evaluate potential confounding by shared susceptibility to the 2 diagnoses. Methods: The …

Depression has been reported in several studies to be more common in Parkinson's disease
(PD) patients than in the general population, and there may be overlap in the …