Immunogenic cell death and DAMPs in cancer therapy

DV Krysko, AD Garg, A Kaczmarek, O Krysko… - Nature reviews …, 2012 - nature.com
Although it was thought that apoptotic cells, when rapidly phagocytosed, underwent a silent
death that did not trigger an immune response, in recent years a new concept of …

HHV-8-negative, idiopathic multicentric Castleman disease: novel insights into biology, pathogenesis, and therapy

DC Fajgenbaum, F van Rhee… - Blood, The Journal of the …, 2014 - ashpublications.org
Multicentric Castleman's disease (MCD) describes a heterogeneous group of disorders
involving proliferation of morphologically benign lymphocytes due to excessive …

Cutaneous T‐cell lymphoma: 2017 update on diagnosis, risk‐stratification, and management

RA Wilcox - American journal of hematology, 2017 - Wiley Online Library
Disease overview Cutaneous T‐cell lymphomas are a heterogenous group of T‐cell
lymphoproliferative disorders involving the skin, the majority of which may be classified as …

Novel insights and therapeutic approaches in idiopathic multicentric Castleman disease

DC Fajgenbaum - Blood, The Journal of the American Society …, 2018 - ashpublications.org
Castleman disease (CD) describes a heterogeneous group of hematologic disorders that
share characteristic lymph node histopathology. Patients of all ages present with either a …

Cutaneous T‐cell lymphoma: 2016 update on diagnosis, risk‐stratification, and management

RA Wilcox - American journal of hematology, 2016 - Wiley Online Library
Disease overview: Cutaneous T‐cell lymphomas are a heterogenous group of T‐cell
lymphoproliferative disorders involving the skin, the majority of which may be classified as …

Evolving insights in the pathogenesis and therapy of cutaneous T‐cell lymphoma (mycosis fungoides and Sezary syndrome)

HK Wong, A Mishra, T Hake… - British journal of …, 2011 - Wiley Online Library
Cutaneous T‐cell lymphomas (CTCL) are a heterogeneous group of malignancies derived
from skin‐homing T cells. The most common forms of CTCL are Mycosis Fungoides (MF) …

Crosstalk between apoptosis and autophagy: molecular mechanisms and therapeutic strategies in cancer

A El-Khattouti, D Selimovic, Y Haikel… - Journal of cell …, 2013 - journals.sagepub.com
Both apoptosis and autophagy are highly conserved processes that besides their role in the
maintenance of the organismal and cellular homeostasis serve as a main target of tumor …

[HTML][HTML] Induction of autophagy-dependent apoptosis in cancer cells through activation of ER stress: an uncovered anti-cancer mechanism by anti-alcoholism drug …

X Zhang, P Hu, SY Ding, T Sun, L Liu… - American Journal of …, 2019 - ncbi.nlm.nih.gov
Due to its potent anticancer activity, there is interest in repurposing of the FDA-approved anti-
alcoholism drug, disulfiram (DSF). DSF forms potent complexes with copper (DSF/Cu) that …

[HTML][HTML] Inhibition of thioredoxin 1 leads to apoptosis in drug-resistant multiple myeloma

PV Raninga, G Di Trapani, S Vuckovic, M Bhatia… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Multiple myeloma (MM) is a hematological malignancy characterized by the aberrant
accumulation of clonal plasma cells in the bone marrow. Despite recent advancement in anti …

Extracellular vesicles of multiple myeloma cells utilize the proteasome inhibitor mechanism to moderate endothelial angiogenesis

M Zarfati, I Avivi, B Brenner, T Katz, A Aharon - Angiogenesis, 2019 - Springer
Bone marrow microenvironment is known to support angiogenesis, thus contributing to
progression of multiple myeloma (MM). Bortezomib, a proteasome inhibitor (PI) widely used …